[article] in Journal of the American Podiatric Medical Association > vol. 107, 4 (Juillet- août 2017) . - p. 272-279 Titre : | Does baseline hemoglobin a1c level predict diabetic foot ulcer outcome or wound healing time? | Type de document : | article de périodique | Auteurs : | Lourdes Vella, Auteur ; [et al.], Auteur | Année de publication : | 2017 | Article en page(s) : | p. 272-279 | Langues : | Anglais (eng) | Descripteurs (mots clés) : | [Thésaurus Mesh]Diabète de type 2 [Thésaurus Mesh]Hémoglobine A glycosylée [Thésaurus Mesh]Pied diabétique [Thésaurus Mesh]Présentations de cas [Thésaurus Mesh]Signes et symptômes [Thésaurus HELB]:Paramédical:Niveau initial
| Mots-clés : | hemoglobin A, glycosylated Baseline level signs and symptoms diabetes mellitus, type 2 diabetic foot case reports | Résumé : | Background: We sought to evaluate the relationship between baseline hemoglobin A1c (HbA1c) level and clinical outcomes, including foot ulcer outcome (resolved versus unresolved) and wound-healing time, in individuals with type 2 diabetes.
Methods: A prospective observational study was conducted on 99 patients presenting with a diabetic foot ulceration. Patient and ulcer characteristics were recorded. Patients were followed up for a maximum of 1 year.
Results: After 1 year of follow-up, 77% of ulcers healed and 23% did not heal. Although this study demonstrated that the baseline HbA1c reading was not a significant predictor of foot ulcer outcome (P ¼ .603, resolved versus amputated), on further statistical analyses, when HbA1c was compared with the time taken for complete ulcer healing in the resolved group (n ¼ 77), it proved to be significant (P ¼ .009).
Conclusions: These findings have important implications for clinical practice, especially in an outpatient setting. Improving glycemic control may improve ulcer outcomes. Prediction of outcome may be helpful for health-care professionals in individualizing and optimizing clinical assessment and management of patients. Identification of determinants of outcome could result in improved health outcomes, improved quality of life, and fewer diabetes-related foot complications.
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