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> C > Choriorétinopathie séreuse centrale
Choriorétinopathie séreuse centrale
A visual impairment characterized by the accumulation of fluid under the retina through a defect in the retinal pigment epithelium.
Synonyme(s)
CRSC; Chorio-rétinopathie séreuse centrale; Choriorétinopathie centrale séreuseRelation(s)
- voir aussi au terme générique : [Descripteurs (mots clés)] Rétinopathies
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Accommodation Is Decreased in Eyes with Acute Central Serous Chorioretinopathy / Dmitrii S Maltsev in OVS : Optometry & Vision Science, vol. 99, 9 (septembre 2022)
[article]
in OVS : Optometry & Vision Science > vol. 99, 9 (septembre 2022)
Titre : Accommodation Is Decreased in Eyes with Acute Central Serous Chorioretinopathy Type de document : article de périodique Auteurs : Dmitrii S Maltsev ; Alexei N Kulikov ; Alexander S. Vasiliev ; Jay Chhablani Année de publication : 2022 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]Accommodation oculaire
[Thésaurus Mesh]Choriorétinopathie séreuse centraleRésumé : SIGNIFICANCE: This is a case-control study showing changes in accommodation in eyes with acute central serous chorioretinopathy. We found that decreased accommodative amplitude in the affected eyes may indicate suppression of parasympathetic activity in those eyes as one of the pathophysiological mechanisms controlling choroidal thickness and perfusion. PURPOSE: This study aimed to evaluate the changes of accommodation in patients with acute central serous chorioretinopathy. METHODS: Patients with unilateral central serous chorioretinopathy, with and without foveal involvement, as well as patients after resolution of subretinal fluid and healthy age-matched controls were included. Accommodative amplitude was measured and compared between eyes with active or resolved central serous chorioretinopathy, fellow eyes of active central serous chorioretinopathy individuals, and eyes of controls. Correlation between accommodative amplitude and ocular and demographic parameters was calculated. RESULTS: Nineteen acute central serous chorioretinopathy patients (16 males and 3 females, 38.1 ± 5.1 years) and 17 age-matched controls (13 males and 4 females, 37.2 ± 5.4 years) were included. Accommodative amplitude in the study eyes of central serous chorioretinopathy patients was lower than that in the fellow unaffected eyes (1.25 ± 1.0 and 2.54 ± 0.94 D, respectively; P = .002) or in the eyes of healthy controls (2.41 ± 1.38 D, P = .002). In central serous chorioretinopathy eyes, after resolution of subretinal fluid or without foveal involvement, the median accommodative amplitude was lower than that in fellow eyes (1.6 [95% confidence interval, 0.83 to 1.75] and 2.7 D [95% confidence interval, 1.23 to 3.61], respectively; P = .004). No correlation was found between accommodative amplitude in affected central serous chorioretinopathy eyes and different parameters, except for age (r = −0.47, P = .04). CONCLUSIONS: Acute central serous chorioretinopathy is associated with a substantial reduction of accommodative amplitude. Note de contenu :
Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Analysis of Optical Coherence Tomography in Acute versus Chronic Central Serous Chorioretinopathy / Yanzhen Li in OVS : Optometry & Vision Science, vol.99, 03 (Mars 2022)
[article]
in OVS : Optometry & Vision Science > vol.99, 03 (Mars 2022)
Titre : Analysis of Optical Coherence Tomography in Acute versus Chronic Central Serous Chorioretinopathy Type de document : article de périodique Auteurs : Yanzhen Li ; Jin Pengfei ; Jianmin Lu ; Li Ma ; Xiuhong Qin Année de publication : 2022 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]Choriorétinopathie séreuse centrale
[Thésaurus Mesh]Tomographie par cohérence optiqueMots-clés : choriorétinopathie chronique Résumé : SIGNIFICANCE
Central serous chorioretinopathy (CSC) is a common retinal disease that causes vision loss worldwide. Studying the imaging characteristics of CSC is helpful for the differential diagnosis of diseases. This study analyzed the differences between acute and chronic CSC and provide related information.
PURPOSE
The aim of this study was to describe the optical coherence tomography features in patients with acute and chronic CSC.
METHODS
Sixty-two eyes of 56 patients with CSC were included in the study. Optical coherence tomography was performed to observe the image features. The photoreceptor outer-segment (PROS) thickness above the pigment epithelium detachment (PED) coinciding with the leakage point in fundus fluorescein angiography was measured and compared with the mean PROS thickness outside the PED in acute cases. The SPSS 23.0 software (IBM Co., Chicago, IL) was used for statistical analysis.
RESULTS
Of our 56 patients (62 eyes), 41 (73.21%) were male and 15 (26.79%) were female. There were 53 eyes (85.48%) with acute CSC and 9 eyes (14.52%) with chronic CSC. Besides other common features, the new feature of a high-reflection band in the outer nuclear layer was found to be limited to the macular detachment area. In acute cases, the mean PROS thickness above the retinal pigment epithelium layer protuberance coinciding with the leakage point was 22.7 ± 8.8 μm, which was less than the mean PROS thickness outside the PED at 64.3 ± 21.3 μm (P ≤ .001).
CONCLUSIONS
The high-reflection band in the outer nuclear layer within the serous neurosensory detachment limited to the macular area was a new finding in CSC patients. This finding can be used as an imaging feature to aid in the diagnosis of CSC.Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Combined topical anti-inflammatory and oral acetazolamide in the treatment of central serous chorioretinopathy / Raphael Wuarin in OVS : Optometry & Vision Science, vol. 96, 07 (Juillet 2019)
[article]
in OVS : Optometry & Vision Science > vol. 96, 07 (Juillet 2019)
Titre : Combined topical anti-inflammatory and oral acetazolamide in the treatment of central serous chorioretinopathy Type de document : article de périodique Auteurs : Raphael Wuarin ; Vinodh Kakkassery ; Andrea Consigli ; Daniel Roquelaure ; Athanasios Papanastasiou ; James Scott Schutz ; Gabriele Thumann ; Argyrios Chronopoulos Année de publication : 2019 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]:C:Choriorétinopathie séreuse centrale:Choriorétinopathie séreuse centrale / thérapie
[Thésaurus Mesh]Choriorétinopathie séreuse centrale
[Thésaurus Mesh]Épithélium pigmentaire de la rétineRésumé : SIGNIFICANCE Central serous chorioretinopathy (CSCR) is still a therapeutic challenge with no criterion standard treatment. However, anatomic changes at the level of the retinal pigment epithelium could prove of predictive value in the course of the disease for selective treatment in cases of increased risk of chronicity.
PURPOSE This pilot study analyzes the efficacy for treating acute CSCR with combined systemic acetazolamide 250 mg twice a day and nepafenac 0.1% eye drops three times a day in comparison with an untreated control group. It also evaluates the presence a pigment epithelial detachment (PED) as a risk factor for chronic CSCR.
METHODS Nineteen consecutive patients (group 1) with new or new onset of recurrent CSCR were treated with oral acetazolamide and nepafenac eye drops for at least 2 months. A control group of 14 patients (group 2) with new or new onset of recurrent CSCR were untreated while under regular observation for 4 months. Primary end points were central macular thickness and best-corrected visual acuity after 4 months. Secondary end points were complete regression of subretinal fluid at 3 months and association of PED at baseline with recurrent or chronic CSCR imaged by optical coherence tomography.
RESULTS Group 1 showed significantly faster resolution of subretinal fluid with a mean central macular thickness at 4 months of 271 ± 85 μm compared with 322 ± 79 μm for group 2 (P < .05), but with no functional benefit with a best-corrected visual acuity at 4 months of 0.8 ± 0.2 for group 1 compared with 0.9 ± 0.1 for the control group (P < .05). Patients with a small flat PED were at a higher risk of developing chronic CSCR compared with patients with a dome-shaped or no PED (P < .05).
CONCLUSIONS Central serous chorioretinopathy remains a therapeutic challenge. This pilot study shows faster resolution of subretinal fluid with treatment but without functional benefit compared with observation. The presence of small, flat PED was associated with development of chronic CSCR.Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Erdafitinib-induced Central Serous Chorioretinopathy / Richard T. Claiborne in OVS : Optometry & Vision Science, vol. 99, 01 (Janvier 2022)
[article]
in OVS : Optometry & Vision Science > vol. 99, 01 (Janvier 2022)
Titre : Erdafitinib-induced Central Serous Chorioretinopathy Type de document : article de périodique Auteurs : Richard T. Claiborne ; Grace L. Tsan Année de publication : 2022 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]Choriorétinopathie séreuse centrale
[Thésaurus Mesh]Dépistage visuel
[Thésaurus Mesh]Ophtalmologie
[Thésaurus HELB]:Paramédical:Effets indésirables des médicamentsMots-clés : erdafitinib Résumé : SIGNIFICANCE
Erdafitinib is the first fibroblast growth factor receptor inhibitor approved by the U.S. Food and Drug Administration in April 2019 for the treatment of locally advanced and unresectable or metastatic urothelial carcinoma. Central serous chorioretinopathy is a common ocular adverse effect requiring frequent monitoring with ophthalmic examination.
PURPOSE
This study aimed to increase awareness of erdafitinib-induced central serous chorioretinopathy, highlight erdafitinib dose management guidelines, and emphasize the importance of collaborating with oncologists to prevent adverse visual consequences.
CASE REPORT
An 80-year-old patient with an advanced urothelial cancer with fibroblast growth factor receptor mutations developed central serous chorioretinopathy when he was treated with daily 8 mg of erdafitinib. The erdafitinib-induced central serous chorioretinopathy resolved completely after the discontinuation of erdafitinib. He was then treated with daily 6 mg of erdafitinib and again developed central serous chorioretinopathy, which resolved completely upon discontinuation of the medication. The patient then decided to stop treatment with erdafitinib.
CONCLUSIONS
Erdafitinib, a potent tyrosine kinase receptor inhibitor of fibroblast growth factor receptors 1 to 4, demonstrates antitumor activity in advanced urothelial carcinoma with fibroblast growth factor receptor mutations with a response rate of approximately 40%. However, central serous chorioretinopathy develops in 25% of patients treated with a daily 8-mg dose of erdafitinib. Although most mild to moderate erdafitinib-induced central serous chorioretinopathies resolve with dose interruption or reduction, occasionally discontinuation of the medication is necessary. Therefore, careful coordination with oncologists is important to assess the impact of erdafitinib on vision, quality of life, and survival prognosis.Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Serous retinal detachment causes a transient reduction on spectral domain oct estimates of ganglion cell layer thickness / Ki Yup Nam in OVS : Optometry & Vision Science, vol. 96, 03 (Mars 2019)
[article]
in OVS : Optometry & Vision Science > vol. 96, 03 (Mars 2019) . - p. 156-163
Titre : Serous retinal detachment causes a transient reduction on spectral domain oct estimates of ganglion cell layer thickness Type de document : article de périodique Auteurs : Ki Yup Nam, Auteur ; Jung Yeul Kim, Auteur Année de publication : 2019 Article en page(s) : p. 156-163 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]Cellules ganglionnaires rétiniennes
[Thésaurus Mesh]Choriorétinopathie séreuse centrale
[Thésaurus Mesh]Collecte de données
[Thésaurus Mesh]Décollement de la rétine
[Thésaurus Mesh]Dépistage visuel
[Thésaurus Mesh]Tomographie par cohérence optiqueRésumé : SIGNIFICANCE During the acute stage of central serous chorioretinopathy (CSC) with retinal elevation, the spectral domain optical coherence tomography (SD-OCT) estimate of ganglion cell layer complex thickness is reduced. Thickness returns to normal after resolution of the event. Measurement error is at least partially responsible for this effect. The reduction in ganglion cell layer complex thickness does not represent atrophy and is not predictive of a poor outcome.
PURPOSE We investigated the effects of serous retinal detachment on the ganglion cell layer complex analysis (GCA) by SD-OCT in CSC patients during the acute episodes and after resolution of fluid.
METHODS We retrospectively reviewed medical records of 30 patients who visited the hospital with a first episode of CSC. We analyzed GCA maps using SD-OCT (Cirrus; Carl Zeiss Meditec, Dublin, CA) at the initial visit with serous retinal elevation and after the absorption of subretinal fluid. For repeatability analysis, we used the intraclass correlation and repeatability coefficient from two consecutive measurements 5 minutes apart in 12 patients.
RESULTS At the initial visit, an average thickness of ganglion cell layer complex was thinner than that measured in the fellow eye (67.4 ± 27.4 μm), but after the absorption of subretinal fluid, it normalized to 87.0 ± 6.7 μm; the difference was statistically significant. The intraclass correlation and repeatability coefficient were low during the period of serous elevation but normalized after fluid resorption. Abnormalities of GCA resulted from the segmentation error of ganglion cell layer and inner plexiform layer during the acute phase of CSC.
CONCLUSIONS Serous retinal detachment can affect the GCA and repeatability measurements of the GCA. Clinicians should consider this finding when using the GCA measurement in the diagnosis and management of the patients with retinal contour changes such as retinal elevation including CSC.Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire