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Descripteurs (mots clés)
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rho-Associated Kinases
A group of intracellular-signaling serine threonine kinases that bind to RHO GTP-BINDING PROTEINS. They were originally found to mediate the effects of rhoA GTP-BINDING PROTEIN on the formation of STRESS FIBERS and FOCAL ADHESIONS. Rho-associated kinases have specificity for a variety of substrates including MYOSIN-LIGHT-CHAIN PHOSPHATASE and LIM KINASES.
Synonyme(s)
Kinase rho; Protéine kinases ROCK; ROCK Protein Kinases; ROK Kinase; rho-Associated Coiled-Coil Kinase; rho-Kinase; rho-Associated Kinase 1; Protéine kinases ROCK-1; Protéine kinases ROCK-I; ROCK-I Protein Kinase; p160ROCK; rho-Associated Coiled-Coil Containing Protein Kinase 1; rho-Associated Kinase beta; rho-Associated Kinase 2; Protéine kinases ROCK-2; Protéine kinases ROCK-II; ROCK-II Protein Kinase; p160 rhoA-Binding Kinase ROKalpha; rho-Associated Coiled-Coil Containing Protein Kinase 2; rho-Associated Kinase alpha; rho-Associated Protein Kinase alphaRelation(s)
- voir aussi au terme générique : [Descripteurs (mots clés)] Protein-Serine-Threonine Kinases
- voir aussi au terme générique : [Descripteurs (mots clés)] Protéines et peptides de signalisation intracellulaire
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