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Auteur Javier La Fontaine
Documents disponibles écrits par cet auteur
Ajouter le résultat dans votre panier Affiner la rechercheAre Surrogate Markers for Diabetic Foot Osteomyelitis Remission Reliable? / Peter A. Crisologo in Journal of the American Podiatric Medical Association, vol.111,05 (septembre-octobre 2021)
[article]
in Journal of the American Podiatric Medical Association > vol.111,05 (septembre-octobre 2021)
Titre : Are Surrogate Markers for Diabetic Foot Osteomyelitis Remission Reliable? Type de document : article de périodique Auteurs : Peter A. Crisologo ; Matthew Malone ; Javier La Fontaine ; Kavita Bhavan ; Adam Nichols ; Lawrence A. Lavery Année de publication : 0021 Langues : Anglais (eng) Descripteurs (mots clés) : [Thésaurus HELB]:Paramédical:Rémission
[Thésaurus Mesh]Infections des tissus mous
[Thésaurus Mesh]Marqueurs biologiques
[Thésaurus Mesh]Ostéomyélite
[Thésaurus Mesh]Pied diabétique
[Thésaurus Mesh]Revue de la littérature
[Thésaurus Mesh]Ulcère du piedRésumé : Background
We aimed to evaluate surrogate markers commonly used in the literature for diabetic foot osteomyelitis remission after initial treatment for diabetic foot infections (DFIs).
Methods
Thirty-five patients with DFIs were prospectively enrolled and followed for 12 months. Osteomyelitis was determined from bone culture and histologic analysis initially and for recurrence. Fisher exact and χ2 tests were used for dichotomous variables and Student t and Mann-Whitney U tests for continuous variables (α = .05).
Results
Twenty-four patients were diagnosed as having osteomyelitis and 11 as having soft-tissue infections. Four patients (16.7%) with osteomyelitis had reinfection based on bone biopsy. The success of osteomyelitis treatment varied based on the surrogate marker used to define remission: osteomyelitis infection (16.7%), failed wound healing (8.3%), reulceration (20.8%), readmission (16.7%), amputation (12.5%). There was no difference in outcomes among patients who were initially diagnosed as having osteomyelitis versus soft-tissue infections. There were no differences in osteomyelitis reinfection (16.7% versus 45.5%; P = .07), wounds that failed to heal (8.3% versus 9.1%; P = .94), reulceration (20.8% versus 27.3%; P = .67), readmission for DFIs at the same site (16.7% versus 36.4%; P = .20), amputation at the same site after discharge (12.5% versus 36.4%; P = .10). Osteomyelitis at the index site based on bone biopsy indicated that failed therapy was 16.7%. Indirect markers demonstrated a failure rate of 8.3% to 20.8%.
Conclusions
Most osteomyelitis markers were similar to markers in soft-tissue infection. Commonly reported surrogate markers were not shown to be specific to identify patients who failed osteomyelitis treatment compared with patients with soft-tissue infections. Given this, these surrogate markers are not reliable for use in practice to identify osteomyelitis treatment failure.Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Are Surrogate Markers for Diabetic Foot Osteomyelitis Remission Reliable? / Peter A. Crisologo in Journal of the American Podiatric Medical Association, vol. 111, 05 (septembre-octobre 2021)
[article]
in Journal of the American Podiatric Medical Association > vol. 111, 05 (septembre-octobre 2021)
Titre : Are Surrogate Markers for Diabetic Foot Osteomyelitis Remission Reliable? Type de document : article de périodique Auteurs : Peter A. Crisologo ; Matthew Malone ; Javier La Fontaine ; Kavita Bhavan ; Adam Nichols ; Lawrence A. Lavery Année de publication : 2021 Langues : Anglais (eng) Descripteurs (mots clés) : [Thésaurus HELB]:Paramédical:Rémission
[Thésaurus Mesh]Marqueurs biologiques
[Thésaurus Mesh]Ostéomyélite
[Thésaurus Mesh]Pied diabétiqueRésumé : Background
We aimed to evaluate surrogate markers commonly used in the literature for diabetic foot osteomyelitis remission after initial treatment for diabetic foot infections (DFIs).
Methods
Thirty-five patients with DFIs were prospectively enrolled and followed for 12 months. Osteomyelitis was determined from bone culture and histologic analysis initially and for recurrence. Fisher exact and χ2 tests were used for dichotomous variables and Student t and Mann-Whitney U tests for continuous variables (α = .05).
Results
Twenty-four patients were diagnosed as having osteomyelitis and 11 as having soft-tissue infections. Four patients (16.7%) with osteomyelitis had reinfection based on bone biopsy. The success of osteomyelitis treatment varied based on the surrogate marker used to define remission: osteomyelitis infection (16.7%), failed wound healing (8.3%), reulceration (20.8%), readmission (16.7%), amputation (12.5%). There was no difference in outcomes among patients who were initially diagnosed as having osteomyelitis versus soft-tissue infections. There were no differences in osteomyelitis reinfection (16.7% versus 45.5%; P = .07), wounds that failed to heal (8.3% versus 9.1%; P = .94), reulceration (20.8% versus 27.3%; P = .67), readmission for DFIs at the same site (16.7% versus 36.4%; P = .20), amputation at the same site after discharge (12.5% versus 36.4%; P = .10). Osteomyelitis at the index site based on bone biopsy indicated that failed therapy was 16.7%. Indirect markers demonstrated a failure rate of 8.3% to 20.8%.
Conclusions
Most osteomyelitis markers were similar to markers in soft-tissue infection. Commonly reported surrogate markers were not shown to be specific to identify patients who failed osteomyelitis treatment compared with patients with soft-tissue infections. Given this, these surrogate markers are not reliable for use in practice to identify osteomyelitis treatment failure.Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire A Comparison of Pathogens in Skin and Soft-Tissue Infections and Pedal Osteomyelitis in Puncture Wound Injuries Affecting the Foot / David H. Truong in Journal of the American Podiatric Medical Association, vol. 112, 06 (Novembre 2022)
[article]
in Journal of the American Podiatric Medical Association > vol. 112, 06 (Novembre 2022)
Titre : A Comparison of Pathogens in Skin and Soft-Tissue Infections and Pedal Osteomyelitis in Puncture Wound Injuries Affecting the Foot Type de document : article de périodique Auteurs : David H. Truong ; Javier La Fontaine ; Matthew Malone ; Dane K. Wukich ; Kathryn E. Davis ; Lawrence A. Lavery Année de publication : 2022 Langues : Anglais (eng) Descripteurs (mots clés) : [Thésaurus Mesh]Étude comparative
[Thésaurus Mesh]Infection de plaie
[Thésaurus Mesh]Morsures et piqûres d'insectes
[Thésaurus Mesh]Pathogènes transmissibles par le sang
[Thésaurus Mesh]Pied diabétique
[Thésaurus Mesh]Ulcère du piedMots-clés : Infections de la peau et des tissus mous Résumé : Background: To compare pathogens involved in skin and soft-tissue infections (SSTIs) and pedal osteomyelitis (OM) in patients with and without diabetes with puncture wounds to the foot. Methods: We evaluated 113 consecutive patients between June 1, 2011, and March 31, 2019, with foot infection (SSTIs and OM) from a puncture injury sustained to the foot. Eighty-three patients had diabetes and 30 did not. We evaluated the bacterial pathogens in patients with SSTIs and pedal OM. Results: Polymicrobial infections were more common in patients with diabetes mellitus (83.1% versus 53.3%; P = .001). The most common pathogen for SSTIs and OM in patients with diabetes was Staphylococcus aureus (SSTIs, 50.7%; OM, 32.3%), whereas in patients without diabetes it was Pseudomonas (25%) for SSTIs. Anaerobes (9.4%) and fungal infection (3.1%) were uncommon. Pseudomonas aeruginosa was identified in only 5.8% of people with diabetes. Conclusions: The most common bacterial pathogen in both SSTIs and pedal OM was S aureus in patients with diabetes. Pseudomonas species was the most common pathogen in people without diabetes with SSTIs. Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Current concepts in the surgical management of acute diabetic foot infections / Javier La Fontaine in The Foot, vol.24, 3 (Septembre 2014)
[article]
in The Foot > vol.24, 3 (Septembre 2014) . - 123-127
Titre : Current concepts in the surgical management of acute diabetic foot infections Type de document : article de périodique Auteurs : Javier La Fontaine, Auteur ; Kavita Bhavan, Auteur ; Talal K. Talal, Auteur Article en page(s) : 123-127 Descripteurs (mots clés) : [Thésaurus Mesh]:P:Pied diabétique:Pied diabétique / chirurgie Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité Périodique Erasme - périodiques Périodiques Disponible Current concepts of Charcot foot in diabetic patient / Javier La Fontaine in The Foot, 26 (Mars-mai 2016)
[article]
in The Foot > 26 (Mars-mai 2016) . - p.7-14
Titre : Current concepts of Charcot foot in diabetic patient Type de document : article de périodique Auteurs : Javier La Fontaine Année de publication : 2016 Article en page(s) : p.7-14 Langues : Anglais (eng) Descripteurs (mots clés) : [Thésaurus Mesh]Diabète
[Thésaurus Mesh]Pied diabétiquePermalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité F Périodique Erasme - périodiques Périodiques Disponible F Périodique Erasme - périodiques Périodiques Disponible Effect of Sensory Neuropathy on the Predictive Value of Inflammatory Biomarkers for Osteomyelitis in Diabetic and Nondiabetic Patients with Foot Infections / Easton Ryan in Journal of the American Podiatric Medical Association, vol. 112, 02 (Avril-juin 2022)
PermalinkFracture healing and biomarker expression in a diabetic zucher rat model / Javier La Fontaine in Journal of the American Podiatric Medical Association, vol.104, 5 (Septembre 2014)
PermalinkHigh-Risk Patients with Infected Puncture Wounds and Appropriate Tetanus Prophylaxis / David H. Truong in Journal of the American Podiatric Medical Association, vol. 113, 01 (Janvier 2023)
PermalinkIncidence and Recovery of Acute Kidney Injury in Diabetic and Nondiabetic Patients with Foot Infections / Easton Ryan in Journal of the American Podiatric Medical Association, vol. 112, 06 (Novembre 2022)
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