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Détail de l'auteur
Auteur Ann E. Elsner
Documents disponibles écrits par cet auteur
Ajouter le résultat dans votre panier Affiner la recherche2022 Prentice Award Lecture: Advancing Retinal Imaging and Visual Function in Patient Management and Disease Mechanisms / Ann E. Elsner in OVS : Optometry & Vision Science, vol. 100, 06 (Juin 2023)
[article]
in OVS : Optometry & Vision Science > vol. 100, 06 (Juin 2023)
Titre : 2022 Prentice Award Lecture: Advancing Retinal Imaging and Visual Function in Patient Management and Disease Mechanisms Type de document : article de périodique Auteurs : Ann E. Elsner Année de publication : 2023 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]Dégénérescence maculaire
[Thésaurus Mesh]Dépistage visuel
[Thésaurus Mesh]Diagnostic par imagerie
[Thésaurus Mesh]Histologie
[Thésaurus Mesh]Rétine
[Thésaurus Mesh]Rétinopathie diabétique
[Thésaurus Mesh]Rétinopathies
[Thésaurus HELB]:Optique:œdème maculaire diabétiqueRésumé : SIGNIFICANCE: Patient-based research plays a key role in probing basic visual mechanisms. Less-well recognized is the role of patient-based retinal imaging and visual function studies in elucidating disease mechanisms, which are accelerated by advances in imaging and function techniques and are most powerful when combined with the results from histology and animal models. A patient's visual complaints can be one key to patient management, but human data are also key to understanding disease mechanisms. Unfortunately, pathological changes can be difficult to detect. Before advanced retinal imaging, the measurement of visual function indicated the presence of pathological changes that were undetectable with existing clinical examination. Over the past few decades, advances in retinal imaging have increasingly revealed the unseen. This has led to great strides in the management of many diseases, particularly diabetic retinopathy and macular edema, and age-related macular degeneration. It is likely widely accepted that patient-based research, as in clinical trials, led to such positive outcomes. Both visual function measures and advanced retinal imaging have clearly demonstrated differences among retinal diseases. Contrary to initial thinking, sight-threatening damage in diabetes occurs to the outer retina and not only to the inner retina. This has been clearly indicated in patient results but has only gradually entered the clinical classifications and understanding of disease etiology. There is strikingly different pathophysiology for age-related macular degeneration compared with photoreceptor and retinal pigment epithelial genetic defects, yet research models and even some treatments confuse these. It is important to recognize the role that patient-based research plays in probing basic visual mechanisms and elucidating disease mechanisms, combining these findings with the concepts from histology and animal models. Thus, this article combines sample instrumentation from my laboratory and progress in the fields of retinal imaging and visual function. Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Central Macular Thickness in Diabetic Patients: A Sex-based Analysis / Edmund Arthur in OVS : Optometry & Vision Science, vol. 96, 04 (Avril 2019)
[article]
in OVS : Optometry & Vision Science > vol. 96, 04 (Avril 2019) . - p. 266-275
Titre : Central Macular Thickness in Diabetic Patients: A Sex-based Analysis Type de document : article de périodique Auteurs : Edmund Arthur, Auteur ; Stuart B Young, Auteur ; Ann E. Elsner, Auteur Année de publication : 2019 Article en page(s) : p. 266-275 Langues : Anglais (eng) Langues originales : Anglais (eng) Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Clinically significant macular edema in an underserved population: Association with demographic factors and hemoglobin A1c / Vamsi Parimi in OVS : Optometry & Vision Science, vol. 101, 01 (Janvier 2024)
[article]
in OVS : Optometry & Vision Science > vol. 101, 01 (Janvier 2024)
Titre : Clinically significant macular edema in an underserved population: Association with demographic factors and hemoglobin A1c Type de document : article de périodique Auteurs : Vamsi Parimi ; Ann E. Elsner ; Thomas J. Gast ; Zhongxue Chen ; Karthikeyan Baskaran ; Mastour A. Alhamami ; Taras V. Litvin ; Glen Y Ozawa ; Jorge A. Cuadros Année de publication : 2024 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]Disparités d'accès aux soins
[Thésaurus Mesh]Hémoglobine A glycosylée
[Thésaurus Mesh]Prévalence
[Thésaurus HELB]:Optique:œdème maculaire diabétiqueMots-clés : Œdème maculaire l'hémoglobine A1c œdème maculaire cliniquement significatif ethnie Résumé : SIGNIFICANCE
Suspected clinically significant macular edema (SCSME) from exudates differed among ethnic groups in our underserved population. African American and Asian subjects had higher prevalence than Hispanics and non-Hispanic Caucasians, from the same clinics. Men had higher prevalence than women. Highly elevated blood glucose was frequent and associated with SCSME.
PURPOSE
We investigated the association between the presence of SCSME from exudates and hemoglobin A1c (HbA1c), as well as demographic factors such as age, sex, and ethnic group. Our population was underserved diabetic patients from the same geographic locations. Ethnic groups were White Hispanic, non-Hispanic Caucasian, African American, and Asian, with a high proportion of underrepresented minorities.
METHODS
In a diabetic retinopathy screening study at four community clinics in Alameda County, California, nonmydriatic 45° color fundus images were collected from underserved diabetic subjects following the EyePACS imaging protocol. Images were analyzed for SCSME from exudates by two certified graders. Logistic regression assessed the association between SCSME from exudates and age, sex, ethnic group, and HbA1c.
RESULTS
Of 1997 subjects, 147 (7.36%) had SCSME from exudates. The mean ± standard deviation age was 53.4 ± 10.5 years. The mean ± standard deviation HbA1c level was 8.26 ± 2.04. Logistic regression analysis indicated a significant association between presence of SCSME from exudates and HbA1c levels (p<0.001), sex (p=0.027), and ethnicity (p=0.030). African Americans (odds ratio [OR], 1.63; 95% confidence interval [CI], 1.06 to 2.50; p=0.025) and Asians (OR, 1.63; 95% CI, 1.05 to 2.54; p=0.029) had a higher risk than Hispanics. After adjusting for ethnicity, sex, and age, the odds of developing SCSME from exudates increased by 26.5% with every 1% increase in HbA1c level (OR, 1.26; 95% CI, 1.18 to 1.36; p<0.001).
CONCLUSIONS
In our underserved population, many diabetic patients had very high HbA1c values. Ethnic background (African American > Asians > Hispanics), sex (male > female), and HbA1c level were strong indicators for identifying who is at increased risk of developing SCSME from exudates.Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
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