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Auteur Randall C. Thomas
Documents disponibles écrits par cet auteur
Ajouter le résultat dans votre panier Affiner la rechercheIn Vitro Antibiotic Resistance among Bacteria from the Cornea in the Antibiotic Resistance Monitoring in Ocular MicRoorganisms Surveillance Study / Randall C. Thomas in OVS : Optometry & Vision Science, vol. 98, 09 (Septembre 2021)
[article]
in OVS : Optometry & Vision Science > vol. 98, 09 (Septembre 2021)
Titre : In Vitro Antibiotic Resistance among Bacteria from the Cornea in the Antibiotic Resistance Monitoring in Ocular MicRoorganisms Surveillance Study Type de document : article de périodique Auteurs : Randall C. Thomas ; Ron Melton ; Patrick M. Vollmer ; Penny A. Asbell Année de publication : 2021 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]:K:Kératite:Kératite / traitement médicamenteux
[Thésaurus Mesh]Bactéries
[Thésaurus Mesh]Cornée
[Thésaurus Mesh]Kératite
[Thésaurus Mesh]Résistance bactérienne aux médicamentsRésumé : PURPOSE
This study aimed to report on in vitro susceptibility patterns among corneal isolates collected in the Antibiotic Resistance Monitoring in Ocular micRoorganisms (ARMOR) study.
METHODS
Each year, from 2009 to 2019, Staphylococcus aureus, coagulase-negative staphylococci (CoNS), Streptococcus pneumoniae, Pseudomonas aeruginosa, and Haemophilus influenzae isolates cultured from patients with ocular infections at participating ARMOR sites were submitted to a central laboratory for species confirmation and antibiotic susceptibility testing. In this analysis of corneal isolates, odds ratios for concurrent resistance were based on sample proportions, one-way ANOVA was used to evaluate resistance by patient age, and Cochran-Armitage tests were used to examine changes in antibiotic resistance over time.
RESULTS
A total of 1499 corneal isolates were collected from 61 sites over the 11-year period. Overall, 34.5% (148 of 429) of S. aureus and 41.9% (220 of 525) of CoNS isolates were methicillin resistant and had higher odds ratios for concurrent resistance to azithromycin (17.44 and 5.67), ciprofloxacin (39.63 and 12.81), and tobramycin (19.56 and 19.95), respectively, relative to methicillin-susceptible isolates (P < .001, all); also, a high proportion of methicillin-resistant S. aureus (85.1%) and methicillin-resistant CoNS (81.8%) were multidrug resistant (at least three classes of antibiotics). Resistance among S. pneumoniae isolates was highest for azithromycin (33.1%), whereas P. aeruginosa and H. influenzae isolates demonstrated low resistance overall. Among staphylococci, antibiotic resistance differed by patient age (S. aureus: F = 6.46, P < .001; CoNS: F = 4.82, P < .001), and few small changes in resistance (≤3.60% per year), mostly decreases, were observed over time.
CONCLUSIONS
Although rates of in vitro antibiotic resistance among presumed keratitis isolates obtained in ARMOR seemed stable between 2009 and 2019, resistance among staphylococci and pneumococci remains high (and should be considered when treating keratitis).Note de contenu : Pas de pdf disponible pour l'instant octobre 2021 Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Reconstruction of a Traumatic Partial First-Ray Amputation with the Use of an Induced Pseudosynovial Membrane and Corticocancellous Autograft: A Case Report / Nathaniel L. P. Preston in Journal of the American Podiatric Medical Association, vol. 110, 02 (Mars-avril 2020)
[article]
in Journal of the American Podiatric Medical Association > vol. 110, 02 (Mars-avril 2020)
Titre : Reconstruction of a Traumatic Partial First-Ray Amputation with the Use of an Induced Pseudosynovial Membrane and Corticocancellous Autograft: A Case Report Type de document : article de périodique Auteurs : Nathaniel L. P. Preston ; Trevor E. Black ; Randall C. Thomas Année de publication : 2020 Langues : Anglais (eng) Descripteurs (mots clés) : [Thésaurus HELB]:Paramédical:chirurgie de reconstruction
[Thésaurus HELB]:Paramédical:reconstruction
[Thésaurus Mesh]:A:Amputation traumatique:Amputation traumatique / anatomopathologie
[Thésaurus Mesh]Autogreffes
[Thésaurus Mesh]Avant-pied humain
[Thésaurus Mesh]Métatarse
[Thésaurus Mesh]Présentations de casRésumé : Reconstruction of large bone defects of the metatarsals, whether resulting from trauma, infection, or a neoplastic process, can be especially challenging when attempting to maintain an anatomical parabola and basic biomechanical stability of the forefoot. We present the case of a 42-year-old man with no significant medical history who presented to the emergency department following a severe lawnmower injury to the left forefoot resulting in a large degloving type injury along the medial aspect of the left first ray extending to the level of the medial malleolus. The patient underwent emergent debridement with application of antibiotic bone cement, external fixation, and a negative-pressure dressing. He was subsequently treated with split-thickness skin graft and iliac crest tricortical autograft using a locking plate construct for reconstruction of the distal first ray. Although the patient failed to advance to radiographic osseous union, clinically there was no motion at the attempted fusion site and no pain with ambulation, suggestive of a pseudoarthrosis. The patient has since progressed to full nonpainful weightbearing in regular shoes and has returned to normal activities of daily living. The patient returned to his preinjury level of work and has had complete resolution of all wounds including his split-thickness skin graft donor site. This case shows the potential efficacy of the Masquelet technique for spanning significant traumatic bone defects of the metatarsals involving complete loss of the metatarsophalangeal joint. Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire