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Auteur Stephen J. Vincent
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Ajouter le résultat dans votre panier Affiner la rechercheFluid Reservoir Thickness and Corneal Edema during Open-eye Scleral Lens Wear / Damien Fisher in OVS : Optometry & Vision Science, vol. 97, 09 (Septembre 2020)
[article]
in OVS : Optometry & Vision Science > vol. 97, 09 (Septembre 2020)
Titre : Fluid Reservoir Thickness and Corneal Edema during Open-eye Scleral Lens Wear Type de document : article de périodique Auteurs : Damien Fisher ; Michael J. Collins ; Stephen J. Vincent Année de publication : 2020 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus HELB]:Optique:port de lentilles de contact
[Thésaurus HELB]:Paramédical:Lentille sclérale
[Thésaurus HELB]:Paramédical:Oxygénation
[Thésaurus Mesh]Cornée
[Thésaurus Mesh]Oedème cornéenRésumé : SIGNIFICANCE: There is debate concerning corneal oxygenation during scleral lens wear due to the potential additive hypoxic effect of a lens plus a fluid reservoir. This study investigated the agreement between theoretical models and empirical measurements of scleral lens–induced corneal edema with respect to central fluid reservoir thickness. PURPOSE: The purpose of this study was to examine the effect of altering the fluid reservoir thickness on central corneal edema during short-term open-eye scleral lens wear and to compare these empirical measurements with predictive theoretical models. METHODS: Ten participants (age, 30 ± 4 years) with normal corneas wore highly oxygen-permeable scleral lenses (141 Dk 10−11 cm3 O2 (cm)/[(s) (cm2 ) (mmHg)]) on separate days with either a low (mean, 144; 95% confidence interval [CI], 127 to 160 μm), medium (mean, 487; 95% CI, 443 to 532 μm), or high (mean, 726; 95% CI, 687 to 766 μm) initial fluid reservoir thickness. Epithelial, stromal, and total corneal edema were measured using high-resolution optical coherence tomography after 90 minutes of wear, before lens removal. Data were calculated or extracted from published theoretical models of scleral lens–induced corneal edema for comparison. RESULTS: Scleral lens–induced central corneal edema was stromal in nature and increased with increasing fluid reservoir thickness; mean total corneal edema was 0.69% (95% CI, 0.34 to 1.04%), 1.81% (95% CI, 1.22 to 2.40%), and 2.11% (95% CI, 1.58 to 2.65%) for the low, medium, and high thickness groups, respectively. No significant difference in corneal edema was observed between the medium and high fluid reservoir thickness groups (P = .37). “Resistance in series” oxygen modeling overestimated the corneal edema observed for fluid reservoir thickness values greater than 400 μm. CONCLUSIONS: Scleral lens–induced central corneal edema increases with increasing reservoir thickness, but plateaus at a thickness of around 600 μm, in agreement with recent theoretical modeling that incorporates factors related to corneal metabolism Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Scleral Lens–Induced Corneal Edema after Penetrating Keratoplasty / Kumar Mukesh in OVS : Optometry & Vision Science, vol. 97, 09 (Septembre 2020)
[article]
in OVS : Optometry & Vision Science > vol. 97, 09 (Septembre 2020)
Titre : Scleral Lens–Induced Corneal Edema after Penetrating Keratoplasty Type de document : article de périodique Auteurs : Kumar Mukesh ; Khamar Pooja ; Shetty Rohit ; Stephen J. Vincent Année de publication : 2020 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]Oedème cornéen
[Thésaurus Mesh]Oxygène
[Thésaurus Mesh]Perméabilité
[Thésaurus Mesh]Transplantation de cornée
[Thésaurus HELB]:Optique:lentilles scléralesRésumé : SIGNIFICANCE: Modern highly oxygen-permeable nonfenestrated scleral lenses induce approximately 1 to 2% corneal edema after short periods of lens wear in healthy individuals. This study investigated the magnitude and regional variation in scleral lens-induced central corneal edema after penetrating keratoplasty. PURPOSE: The purpose of this study was to examine the magnitude and regional variation in corneal edema after a short period of scleral lens wear in post–penetrating keratoplasty eyes and a control group of eyes with healthy corneas. METHODS: Nine post–penetrating keratoplasty eyes (nine participants; mean age, 32 years) were fitted with highly oxygen-permeable nonfenestrated scleral lenses (Dk 100 10−11 cm3 O2 (cm)/[(s) (cm2 ) (mmHg)]). Central corneal thickness was measured using Scheimpflug imaging before lens insertion and immediately after lens removal (mean wearing time, 6.2 hours). Corneal edema was quantified across the central 6 mm and compared with data obtained from a historical control group of healthy eyes using a similar experimental paradigm. RESULTS: Post–penetrating keratoplasty eyes exhibited significant corneal edema after lens wear (2.99% [95% confidence interval, 1.13 to 4.85%]) averaged across the central 6 mm (P = .006) and regional variations in edema (P < .001) (greater swelling toward the graft-host junction inferiorly). Compared with healthy eyes, post– penetrating keratoplasty eyes displayed a greater magnitude of corneal edema (by ~3 ) and greater variability in the corneal response (by ~2.5 ). CONCLUSIONS: Scleral lens–induced central corneal edema is greater in post–penetrating keratoplasty eyes and varies regionally compared with healthy corneas after short-term wear. Lens design and fitting factors contributing to hypoxic and mechanical corneal stress should be carefully considered for all post–penetrating keratoplasty scleral lens fits to minimize potential graft rejection or failure in the longer-term. Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
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