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Auteur Grainne Scanlon
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Ajouter le résultat dans votre panier Affiner la rechercheCan Protanopia Be Correctly Diagnosed in Clinical Practice? An Evaluation of Diagnosis by Four Screening Tests / Peter A. Davison in OVS : Optometry & Vision Science, vol. 97, 10 (Octobre 2020)
[article]
in OVS : Optometry & Vision Science > vol. 97, 10 (Octobre 2020)
Titre : Can Protanopia Be Correctly Diagnosed in Clinical Practice? An Evaluation of Diagnosis by Four Screening Tests Type de document : article de périodique Auteurs : Peter A. Davison ; Grainne Scanlon Année de publication : 2020 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]Diagnostic
[Thésaurus Mesh]Étude comparative
[Thésaurus Mesh]Tests de vision
[Thésaurus Mesh]Troubles de la vision des couleursMots-clés : protanopie Résumé : SIGNIFICANCE: Protanopia is a color vision deficiency (CVD) that is unacceptable for certain occupations. This study compares simultaneously for the first time the ability of three recently revised or developed clinical tests of color vision with the Ishihara test to diagnose protanopia from other color vision deficiencies. PURPOSE: The objectives were to examine the ability of four clinical tests to differentiate (1) between protan and deutan CVDs in patients with protanopia and deuteranopia, and (2) protanopes and deuteranopes as “strong” deficiencies. METHODS: The Hardy-Rand-Rittler (4th ed.), City University (3rd ed.), Ishihara, and Mollon-Reffin tests were evaluated against the Oculus Heidelberg Multi-Color anomaloscope for 18 protanopes and 9 deuteranopes. Diagnosis by anomaloscopy was subsequent to administration of screening tests. RESULTS: The Ishihara test misdiagnosed all 18 protanopes as having a deutan deficiency. In contrast, the HardyRand-Rittler and Mollon-Reffin tests correctly identified protan CVD in 100% of protanopes. No screening test was able to reliably diagnose protanopia on the basis of a strong protan CVD. CONCLUSIONS: The Ishihara test is not suitable for screening for protanopia; its failure to diagnose protanopes as having a protan CVD was far greater than that in previous studies. The Hardy-Rand-Rittler and Mollon-Reffin are the most reliable tests for this purpose. None of the screening tests were able to reliably differentiate dichromacy from strongly anomalous trichromacy. Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Investigation of Surrogate Biomarkers Associated with Macular Pigment Status in a Group of Older Irish Adults / Grainne Scanlon in OVS : Optometry & Vision Science, vol. 97, 10 (Octobre 2020)
[article]
in OVS : Optometry & Vision Science > vol. 97, 10 (Octobre 2020)
Titre : Investigation of Surrogate Biomarkers Associated with Macular Pigment Status in a Group of Older Irish Adults Type de document : article de périodique Auteurs : Grainne Scanlon ; John S. Butler ; Daniel McCartney ; Ekaterina Loskutova ; Rose A. Kenny ; James Loughman Année de publication : 2020 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]Anti-inflammatoires
[Thésaurus Mesh]Antioxydants
[Thésaurus Mesh]Macula
[Thésaurus Mesh]Pigment maculaire
[Thésaurus Mesh]Sujet âgéRésumé : SIGNIFICANCE: Macular pigment (MP) confers potent antioxidant and anti-inflammatory effects at the macula; however, its optical density in the eye is not routinely measured in clinical practice. PURPOSE: This study explored a range of surrogate biomarkers including anthropometric, clinical, and plasma measures that may be associated with lower MP optical density (MPOD). METHODS: Two thousand five hundred ninety-four subjects completed a full MP assessment as part of wave 1 of The Irish Longitudinal Study of Aging. Macular pigment optical density was measured using customized heterochromatic flicker photometry. Clinical (blood pressure), plasma (lipoproteins, inflammatory markers), and anthropometric (waist, hip, height, weight) biomarkers were measured for each participant. RESULTS: Mean (standard deviation) MPOD for the study group was 0.223 (0.161), with a range of 0 to 1.08. One-way ANOVA revealed that MPOD was significantly lower among participants with low plasma high-density lipoprotein (HDL; P = .04), raised plasma triglyceride-to-HDL ratio (P = .003), and raised total cholesterol–to–HDL ratio (P = .03). Subjects with an elevated waist circumference (WC) had a significantly lower MPOD (mean, 0.216 [0.159]) compared with those with an ideal WC (mean, 0.229 [0.162]; P = .03). Significant correlates of MPOD on mixed linear model analysis included education, smoking status, and WC. CONCLUSIONS: Higher abdominal fat is associated with lower MPOD in this representative sample of older Irish adults. Although altered lipoprotein profiles (low HDL, raised triglyceride-to-HDL ratio, raised total cholesterol–to– HDL ratio) may affect the transport, uptake, and stabilization of carotenoids in the retina, these plasma biomarkers were not predictive of low MPOD after adjustment for abdominal circumference. Although WC emerged as a viable anthropometric predictor of lower MPOD, its effect size seems to be small. Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
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