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Détail de l'auteur
Auteur Pilar Cañadas
Documents disponibles écrits par cet auteur
Ajouter le résultat dans votre panier Affiner la rechercheCorneal Confocal Analysis after Scleral Lens Wear in Keratoconus Patients: A Pilot Study / Maria Serramito-Blanco in OVS : Optometry & Vision Science, vol. 99, 11 (Novembre 2022)
[article]
in OVS : Optometry & Vision Science > vol. 99, 11 (Novembre 2022)
Titre : Corneal Confocal Analysis after Scleral Lens Wear in Keratoconus Patients: A Pilot Study Type de document : article de périodique Auteurs : Maria Serramito-Blanco ; Pilar Cañadas ; Cesar Villa-Collar ; Gonzalo Carracedo Année de publication : 2022 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]:K:Kératocône:Kératocône / thérapie
[Thésaurus Mesh]Cornée
[Thésaurus Mesh]Kératocône
[Thésaurus Mesh]Projets pilotes
[Thésaurus HELB]:Optique:lentilles sclérales
[Thésaurus HELB]:Optique:port de lentilles de contactMots-clés : confort Résumé : SIGNIFICANCE: Scleral lenses rely on the scleroconjunctival region without bearing the cornea, which could improve the symptoms and modify the corneal nerve plexus morphology. PURPOSE: This study aimed to evaluate symptoms and changes in corneal nerve plexus morphology and density of Langerhans cells in keratoconus patients with and without intrastromal corneal ring before and after scleral lens wear. METHODS: Sixteen scleral lens wearers with keratoconus were recruited for this short-term experimental pilot study. Subjects were divided into two groups: keratoconus group and intrastromal corneal ring segment group. All subjects were examined in two visits: baseline (before scleral lens wear) and after 6 months of scleral lens wear, after lens removal. The Schirmer I test, the Ocular Surface Disease Index, tear breakup time, and in vivo confocal microscopy were evaluated. RESULTS: The mean age was 42.33 ± 11.27 years. A significant decrease in tear breakup time was found in the total group ( P = .01, Wilcoxon) compared with baseline. Ocular Surface Disease Index score had decreased after 6 months of scleral lens wear in the keratoconus with intrastromal corneal ring segment subgroup ( P = .03, Wilcoxon) and in the total group ( P = .001, Wilcoxon). No statistical changes in nerve density, tortuosity, and ramification were found for either the total group or the subgroup. However, the mean nerve length was higher in all groups, especially in the keratoconus subgroup ( P = .03, Wilcoxon) after 6 months of scleral lens wear. Regarding optical density, the total group showed a significant increase after 6 months of wearing ( P = .02, Wilcoxon). Finally, Langerhans cell density was not statistically different in any group. CONCLUSIONS: These results suggest that scleral lens wearing improves the symptoms and increased the mean length nerves after 6 months of wear use in keratoconus patients. Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Effect of Laser-assisted Subepithelial Keratectomy with Mitomycin C on Corneal Optical Density Measured with Confocal Microscopy / Pilar Cañadas in OVS : Optometry & Vision Science, vol. 98, 04 (Avril 2021)
[article]
in OVS : Optometry & Vision Science > vol. 98, 04 (Avril 2021)
Titre : Effect of Laser-assisted Subepithelial Keratectomy with Mitomycin C on Corneal Optical Density Measured with Confocal Microscopy Type de document : article de périodique Auteurs : Pilar Cañadas ; Montserrat Garcia-Gonzalez ; Juan Gros-Otero ; Maria Isabel Alonso Perez ; Rafael Cañones-Zafra ; Miguel A. Teus Année de publication : 2021 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]:C:Cornée:Cornée / chirurgie
[Thésaurus Mesh]Cornée
[Thésaurus Mesh]Kératectomie sous-épithéliale assistée par laser
[Thésaurus Mesh]Microscopie confocaleMots-clés : densité optique cornéenne Résumé : SIGNIFICANCE: The development of confocal microscopy allows one to obtain high-resolution corneal images like
its optical density. Some studies have evaluated the optical density with Scheimpflug cameras in the early
post-operative period after photorefractive keratectomy, but no studies have evaluated the long-term evolution of
optical density after surface ablation when mitomycin C is used.
PURPOSE: This work aimed to study the changes in corneal optical density measured with confocal microscopy in
eyes treated with laser-assisted subepithelial keratectomy (LASEK) and intraoperative mitomycin C (MMC) to
correct myopia.
METHODS: A study of 24 consecutive myopic eyes that underwent LASEK with 0.02% MMC and a control group of
24 healthy nontreated eyes was performed. Optical density was measured using the images by the confocal microscopy
of the Heidelberg Retina Tomograph II with the Rostock Cornea Module. An analysis of confocal microscopy images was
performed using the ImageJ software to obtain the optical density, in gray-scale units (GSU). The optical density of the
stromal bed was evaluated 3 months, 15 months, and 3 years after surgery and was compared with the optical density at
the equivalent depth of the stroma in controls.
RESULTS: The mean values of optical density for the LASEK group were 81.7 ± 9.7, 78.6 ± 11.7, and
73.6 ± 18.7 GSU at 3 months, 15 months, and 3 years, respectively, and it was 61.8 ± 8.2 GSU for the control
group. A statistically higher optical density 3 and 15 months after LASEK with MMC was found compared with controls (P < .001). No significant difference was found in optical density at 3 years post-operatively.
CONCLUSIONS: Our study suggests that, after LASEK with MMC, the anterior corneal stroma has a higher optical
density at 3 and 15 months post-operatively, which gradually returns to normal values 3 years after surgery.Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire