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Auteur Jane A. Bachman Groth
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Ajouter le résultat dans votre panier Affiner la rechercheCase Report: Idiopathic Sclerosing Orbital Inflammation / Jane A. Bachman Groth in OVS : Optometry & Vision Science, vol. 98, 04 (Avril 2021)
[article]
in OVS : Optometry & Vision Science > vol. 98, 04 (Avril 2021)
Titre : Case Report: Idiopathic Sclerosing Orbital Inflammation Type de document : article de périodique Auteurs : Jane A. Bachman Groth ; Gerald J. Harris Année de publication : 2021 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]Diagnostic
[Thésaurus Mesh]ThérapeutiqueMots-clés : inflammation orbitaire sclérosante idiopathique syndrome d'inflammation orbitaire idiopathique Résumé : SIGNIFICANCE: Idiopathic sclerosing orbital inflammation (ISOI) is characterized by insidious, chronic, progressive inflammation and fibrosis that damage ocular structures and produce a mass effect. This case highlights
the challenges in diagnosis and management of ISOI, as well as the associated ocular morbidities, including potential vision loss.
PURPOSE: The purpose of this study was to provide education regarding a rare condition that exhibits variable presentation and has an unpredictable success rate with regard to treatment paradigm. Improved therapeutic options
are promising. Ultimately, early detection and management are key and may allow for better visual outcome.
CASE REPORT: A 46-year-old woman presented with complaints of chronic right-sided facial headaches and eye
pain and gradual right globe prominence over the previous 6 months. Worsening vision and decreased right peripheral visual field were also noted. Upon examination, an afferent pupillary defect and florid disc edema were evident. Imaging studies revealed an orbital and extraorbital infiltrative mass involving the right orbital apex,
inferior orbital fissure, pterygopalatine fossa, and cavernous sinus. Right anterior orbitotomy with biopsy revealed
fragments of fibroconnective and adipose tissue with sclerosis and chronic focal inflammation, consistent with
ISOI. Treatment included intravenous methylprednisone, followed by oral prednisone, beginning at 60 mg/d with
a slow taper thereafter. Signs and symptoms improved dramatically and eventually resolved. Vision significantly
improved, and the afferent pupillary defect resolved. The patient remained asymptomatic at 3-month follow-up.
CONCLUSIONS: Idiopathic sclerosing orbital inflammation is difficult to diagnose and manage. No large studies
exist because of the rare nature of the disease. Slowly progressive, nonspecific signs and symptoms may delay recognition and treatment. Orbital imaging and histopathologic analysis are critical for definitive diagnosis. Conventional treatment with corticosteroids is not uniformly successful, but newer combined therapy options can
improve outcomes. Early identification and treatment are key to management and ultimate preservation of function
and visionPermalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire The Impact of Axial Eye Growth on Foveal Avascular Zone Measurements in Children / Rachel E. Linderman in OVS : Optometry & Vision Science, vol. 99, 02 (février 2022)
[article]
in OVS : Optometry & Vision Science > vol. 99, 02 (février 2022)
Titre : The Impact of Axial Eye Growth on Foveal Avascular Zone Measurements in Children Type de document : article de périodique Auteurs : Rachel E. Linderman ; Elizabeth Heffernan ; Samantha Ferrante ; Jane A. Bachman Groth ; Joseph Carroll Année de publication : 2022 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]Enfant
[Thésaurus Mesh]OptométrieRésumé : SIGNIFICANCE
Foveal avascular zone (FAZ) area is a frequently used biomarker in diseases impacting the retinal vasculature in pediatric populations. Variation in axial length between individuals results in differences in lateral image scale, which affect the accuracy of FAZ area measurements. Accordingly, changes in axial length over time within individual children would affect estimates of FAZ area change.
PURPOSE
This study aimed to quantify how changes in axial length over time affect estimates of FAZ area change using optical coherence tomography angiography (OCT-A) images.
METHODS
Twenty pediatric participants (<18 years old) and 40 adult participants were imaged on Optovue's Avanti system (Fremont, CA) and had axial length measurements acquired at two time points. The FAZ was segmented twice using the OCT-A image at each time point. Foveal avascular zone area was estimated at both time points using the assumed/fixed axial length of the OCT-A device (unscaled) and using the participant's axial length (scaled). Changes in FAZ area over time were compared between the pediatric and adult groups using both unscaled and scaled data.
RESULTS
The average ± standard deviation follow-up time was 3.35 ± 1.66 years for the pediatric group and 2.90 ± 1.65 years for the adult group. Using unscaled data, FAZ area seemed to decrease between visits in the pediatric group (P = .004), whereas the FAZ area increased between visits in the adult group (P = .003). When correctly scaled data were used, the FAZ area still increased between visits for the adult group (P < .001), although the FAZ area no longer showed a significant change between visits for the pediatric group (P = .37). When comparing the normalized FAZ area change across visits between unscaled and scaled data, a significant difference was found between the adult and pediatric groups (P < .001).
CONCLUSIONS
Scaled data should be used when measuring FAZ area in pediatric populations, especially in longitudinal studies.Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire