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Auteur Dipali Purohit
Documents disponibles écrits par cet auteur
Ajouter le résultat dans votre panier Affiner la rechercheAssessment and Correlation of Corneal Endothelial Cell Changes in Different Stages of Keratoconus in Non–contact Lens Wearers / Zalak Shah in OVS : Optometry & Vision Science, vol. 98, 11 (Novembre 2021)
[article]
in OVS : Optometry & Vision Science > vol. 98, 11 (Novembre 2021)
Titre : Assessment and Correlation of Corneal Endothelial Cell Changes in Different Stages of Keratoconus in Non–contact Lens Wearers Type de document : article de périodique Auteurs : Zalak Shah ; Neha Shilpy ; Dipali Purohit ; Shwetambari Singh Année de publication : 2021 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]:K:Kératocône:Kératocône / épidémiologie
[Thésaurus Mesh]Étude comparative
[Thésaurus Mesh]Kératocône
[Thésaurus Mesh]Optométrie
[Thésaurus HELB]:Optique:Cellules endothéliales cornéennesRésumé : SIGNIFICANCE
The endothelial changes in keratoconus are of interest because these can affect the surgical plan in management. Previously, many studies have evaluated the endothelium in eyes with keratoconus, but there is no common consensus on change in endothelial cell density (ECD) with studies showing variable results.
PURPOSE
This study aimed to compare and correlate endothelial cell parameters in different stages of keratoconus using specular microscope.
METHODS
This cross-sectional, cohort, comparative study included 162 eyes of 96 patients with keratoconus in one or both eyes. Corneal endothelial cell parameters were assessed with SP-1P specular microscope (Topcon Co., Tokyo, Japan). Corneal topography and thickness data were obtained from Sirius tomographer (Costruzione Strumenti Oftalmici, Florence, Italy). Eyes were divided into keratoconus stage 0 to 4 according to ABCD classification. Comparison and correlation of endothelial cell parameters in different stages were done.
RESULTS
There were 21.6% eyes (35) in stage 0, 29.6% eyes (48) in stage 1, 29.0% eyes (47) in stage 2, and 19.8% eyes (32) in stage 3 of keratoconus. Measurement was not possible in stage 4 keratoconus. Among the stages 0, 1, 2, and 3, the ECD was 3024, 3051, 3025, and 3043 cells/mm2; coefficient of variation was 27.2, 27.6, 26.8, and 27.4; and frequency of hexagon cells was 61.5, 63.7, 63.3, and 62.3, respectively (P > .05). The number of analyzed cells was 232, 209, 185, and 169 in stages 0, 1, 2, and 3, respectively (P < .001). No significant difference was found in minimum, maximum, and average cell area between the stages (P > .05). A weak Spearman rank correlation of ECD, coefficient of variation, and frequency of hexagon cells was found between eyes with keratoconus stages 0 and 1 and stages 2 and 3 (r = −0.05, P = .65; r = −0.11, P = .37; r = 0.05, P = .67, respectively). No significant correlation was found in the number of cells analyzed and minimum, maximum, and average cell area between the stages (P > .05).
CONCLUSIONS
Endothelial cell parameters do not show any significant changes and correlation up to stage 3 of keratoconus in non–contact lens wearers.Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Prevalence of Corneal Topographic Patterns in Ectatic Corneal Diseases / Zalak Shah in OVS : Optometry & Vision Science, vol. 99, 07 (Juillet 2022)
[article]
in OVS : Optometry & Vision Science > vol. 99, 07 (Juillet 2022)
Titre : Prevalence of Corneal Topographic Patterns in Ectatic Corneal Diseases Type de document : article de périodique Auteurs : Zalak Shah ; Shwetambari Singh ; Neha Shilpy ; Dipali Purohit Année de publication : 2022 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]Diagnostic
[Thésaurus Mesh]Kératocône
[Thésaurus Mesh]Optométrie
[Thésaurus Mesh]Topographie cornéenneMots-clés : ectasie corneenne maladie de la cornée Résumé : SIGNIFICANCE: The article highlights various topographic patterns and their prevalence in a large spectrum of ectatic corneal diseases (ECDs). Knowledge of these patterns can help clinicians for quicker diagnosis and selection of appropriate contact lens design. PURPOSE: This study aimed to determine various corneal topography patterns and their prevalence in patients with ECDs who visited a tertiary eye hospital in western India. METHODS: Keratoconus, pellucid marginal degeneration, keratoglobus, and post–refractive surgery progressive corneal ectasia are considered under ECDs. This cross-sectional retrospective study reviewed records of 632 consecutive patients with clinical ECDs at their first presentation. The right eye was considered for pattern analysis. In cases with suspected or forme fruste ectasia in the right eye, the fellow eye was considered. A sagittal map with standard scale of Atlas 9000 topographer (Carl Zeiss Meditec AG, Jena, Germany) was used for pattern analysis. They were classified into 18 categories and grouped under five groups. The prevalence of these patterns was calculated and assessed with 95% confidence interval (CI). RESULTS: The mean ± SD age of patients was 23.6 ± 8.2 years. The highest prevalence was of asymmetric patterns (39.6% [95% CI, 35.7 to 43.5%]; asymmetric bowtie [AB] with steepest radial axis index [SRAX], 18.8%; AB with inferior steep, 16.0%; AB with superior steep [SS], 3.2%; symmetric bowtie with SRAX, 1.6%) and of central or paracentral patterns (28.6% [95% CI, 25.1 to 32.3%]; inferior steep, 12.2%; heart, 7.4%; oval, 4.1%; symmetric bowtie, 2.4%; round, 1.6%; irregular, 0.9%) followed by advanced patterns (17.3% [95% CI, 14.4 to 20.4%; nonmeasurable, 5.4%; globus, 4.9%; indiscriminate, 7.0%). The peripheral patterns were 11.7% (95% CI, 9.3 to 14.4%) (claw, 6.3%; junctional, 3.2%; butterfly, 1.9%; SS, 0.3%). Rare patterns were 2.8% (95% CI, 1.7 to 4.5%) (superior [junctional, claw, and heart], AB with SS with SRAX, and AB with SRAX located temporally). CONCLUSIONS: Asymmetric and central or paracentral are the most common patterns in our study. The higher prevalence of advanced patterns indicates the need for earlier diagnosis of ECDs in our population. The peripheral patterns also have significant prevalence Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
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