Titre : | Clinical Report: Correlation of Serum Vitamins and Chalazion |
Type de document : | article de périodique |
Auteurs : | Haixia Cheng ; Xuehua Lv ; Jiaqi Yao ; Zhijun Chen |
Année de publication : | 2022 |
Langues : | Français (fre) |
Descripteurs (mots clés) : | [Thésaurus Mesh]Asie [Thésaurus Mesh]Carence en vitamine A [Thésaurus Mesh]Chalazion [Thésaurus Mesh]Enfant [Thésaurus Mesh]Maladies de la paupière
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Mots-clés : | lésion inflammatoire de la paupière |
Résumé : | SIGNIFICANCE
We demonstrate the clinical correlation between the vitamin A level with chalazion in East Chinese children. Vitamin A deficiency is likely to be a potential cause of childhood chalazion.
PURPOSE
Chalazion is the most common lid inflammatory lesion of the eyelid, which can be caused by retention of tarsal gland secretions. Studies have revealed that vitamin deficiency is an essential risk factor for children with chalazion. In this study, we measured the serum levels of vitamin A and 25-hydroxyvitamin D (25(OH)D), in patients with chalazion.
METHODS
The study included 180 subjects (90 patients with chalazion and 90 control healthy subjects) with an average age of 4.13 ± 2.01 years, and 47.8% of whom were female. Serums came from blood samples collected and used to measure the levels of vitamin A and 25(OH)D.
RESULTS
Both groups had statistically similar baseline characteristics, including age and body mass index. The average serum vitamin A levels in patients with chalazion (0.54 ± 0.15 μmol/L) were significantly lower than in their control counterparts (0.60 ± 0.15 μmol/L; P = .01). There was no significant difference in the serum 25(OH)D levels between the patients (70.15 ± 19.73 nmol/L) and control subjects (71.64 ± 24.46 nmol/L). The percentage of vitamin A deficiency in chalazion group (52.2%) was much higher than the control counterparts (28.6%; P = .001). The percentage of 25(OH)D deficiency showed no significant difference between patients with chalazion and control subjects (58.9 vs. 56.7%).
CONCLUSIONS
Low serum vitamin A was significantly associated with chalazion in children. The serum 25(OH)D level exhibited no correlation with chalazion. |
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