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Descripteurs (mots clés)
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Poly(alcool vinylique)
A polymer prepared from polyvinyl acetates by replacement of the acetate groups with hydroxyl groups. It is used as a pharmaceutic aid and ophthalmic lubricant as well as in the manufacture of surface coatings artificial sponges, cosmetics, and other products.
Synonyme(s)
Alcool polyvinylique; Poly alcool de vinyle; Polyalcool de vinyle; Polyalcool vinyliqueRelation(s)
- voir aussi au terme générique : [Descripteurs (mots clés)] Alcools
- voir aussi au terme générique : [Descripteurs (mots clés)] Polyvinyles
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Uptake and release of polyvinyl alcohol from hydrogel daily disposable contact lenses / Chau-Min Phan in OVS : Optometry & Vision Science, vol. 96, 03 (Mars 2019)
[article]
in OVS : Optometry & Vision Science > vol. 96, 03 (Mars 2019)
Titre : Uptake and release of polyvinyl alcohol from hydrogel daily disposable contact lenses Type de document : article de périodique Auteurs : Chau-Min Phan ; Laksman Subbaraman ; Lyndon Jones Année de publication : 2019 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]:S:Syndromes de l'oeil sec:Syndromes de l'oeil sec / thérapie
[Thésaurus Mesh]Collecte de données
[Thésaurus Mesh]Hydrogel
[Thésaurus Mesh]Lentilles de contact
[Thésaurus Mesh]Poly(alcool vinylique)
[Thésaurus HELB]:Optique:Lentille jetableRésumé : SIGNIFICANCE Polyvinyl alcohol is a wetting agent that could reduce the symptoms of dry eye and contact lens discomfort. Currently, only one lens type, nelfilcon A (DAILIES AquaComfort Plus), releases polyvinyl alcohol. The concept of releasing this agent from contact lenses could be applied to other lens materials.
PURPOSE The purpose of this study was to measure the release of polyvinyl alcohol from commercially available hydrogel daily disposable contact lenses using refractive index and iodine-borate methods.
METHODS Etafilcon A, omafilcon A, and nelfilcon A were soaked in phosphate-buffered saline and 0.2% trifluoroacetic acid/acetonitile for 24 hours to remove residual blister pack components. The lenses were then incubated in a 10-mg/mL solution of polyvinyl alcohol for 24 hours. After the incubation period, the lenses were placed in 2 mL of phosphate-buffered saline. At specified time intervals, t = 0.5, 1, 2, 4, 8, 12, and 24 hours, the samples were evaluated using refractive index and an iodine-borate assay. Polyvinyl alcohol uptake was determined by extracting the lenses with methanol for 24 hours.
RESULTS There were no differences in the uptake of polyvinyl alcohol between lens types (P > .05). The release of this wetting agent for all lens types followed a burst-plateau profile after the first 30 minutes (P > .05). Nelfilcon A had a slightly higher release of polyvinyl alcohol (P < .05) than did etafilcon A but was similar to omafilcon A (P > .05).
CONCLUSIONS The results suggest that the contact lenses tested in this study have similar efficiency in delivering polyvinyl alcohol.Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
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