Titre : | Small Full-thickness Macular Hole Treated with Topical Dorzolamide and Bevacizumab Intravitreal Injections |
Type de document : | article de périodique |
Auteurs : | Estephania Feria Anzaldo ; Sophia El Hamichi ; Aaron Gold ; Azeema Latiff ; Audina M. Berrocal ; Timothy Murray |
Année de publication : | 2021 |
Langues : | Français (fre) |
Descripteurs (mots clés) : | [Thésaurus Mesh]:P:Perforations de la rétine:Perforations de la rétine / thérapie [Thésaurus Mesh]Bévacizumab [Thésaurus Mesh]Macula [Thésaurus Mesh]Perforations de la rétine
|
Mots-clés : | dorzolamide topique |
Résumé : | SIGNIFICANCE
This article reports two cases reported of combined treatment with topical dorzolamide and intravitreal bevacizumab injections, successfully treating small full-thickness macular hole without the need for traditional macular hole surgery.
PURPOSE
This study aimed to report the potential effectiveness of combination treatment with topical dorzolamide and bevacizumab intravitreal injection therapy for small macular holes.
CASE REPORTS
Case 1 was a 68-year-old woman presented with distorted and decreased vision in her right eye for 9 months. Fundus examination showed a full-thickness macular hole, which was confirmed with spectral domain optical coherence tomography measuring 96 μm. Treatment with topical dorzolamide and intravitreal bevacizumab 1.25 mg/0.05 mL injections was initiated. Spectral domain optical coherence tomography showed gradual improvement of the full-thickness macular hole with complete hole closure and visual improvement in just 1 month. Case 2 was a 73-year-old woman who presented with distorted and decreased vision in her right eye for 8 months. Fundus examination showed a full-thickness macular hole in the right eye, confirmed with spectral domain optical coherence tomography, measuring 76 μm. Treatment with topical dorzolamide and intravitreal bevacizumab 1.25 mg/0.05 mL injections was initiated. Spectral domain optical coherence tomography showed gradual improvement of the full-thickness macular hole with complete closure at 2 months and improvement in visual acuity.
CONCLUSIONS
The combination of topical dorzolamide and bevacizumab intravitreal injection is a reasonable consideration for small macular holes with vascular components before considering surgery. Both cases had early macular closure in less than 3 months. |
Permalink : | https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= |