A partir de cette page vous pouvez :
Retourner au premier écran avec les dernières notices... |
Détail de l'auteur
Auteur Gene Mirkin
Documents disponibles écrits par cet auteur
Ajouter le résultat dans votre panier Affiner la rechercheAn Unusual Pediatric Manifestation of the Herpes Simplex Virus / Mo Esmaili in Journal of the American Podiatric Medical Association, vol. 112, 04 (Juillet 2022)
[article]
in Journal of the American Podiatric Medical Association > vol. 112, 04 (Juillet 2022)
Titre : An Unusual Pediatric Manifestation of the Herpes Simplex Virus Type de document : article de périodique Auteurs : Mo Esmaili ; Gary W. Procop ; Gene Mirkin ; Xingpei Hao Année de publication : 2022 Langues : Anglais (eng) Descripteurs (mots clés) : [Thésaurus Mesh]Enfant
[Thésaurus Mesh]Herpès labial
[Thésaurus Mesh]Pied
[Thésaurus Mesh]SimplexvirusRésumé : Herpetic whitlow is a viral infection of the fingers or toes caused by the herpes simplex virus. Herpes simplex virus is a common pathogen that causes infections in any cutaneous or mucocutaneous surface, most commonly gingivostomatitis or genital herpes. However, infection of the digits is also infrequently reported. Herpetic whitlow occurs when the virus infects the distal phalanx of the fingers or toes by means of direct inoculation, causing pain, swelling, erythema, and vesicle formation. The proper diagnosis is important because the condition can mimic various other podiatric abnormalities such as paronychia, bacterial cellulitis, or even embolic disease. Improper diagnosis often leads to unnecessary work-up, antibiotic therapy, or even surgical intervention. This case will help illuminate the clinical presentation of herpetic whitlow in an atypical location, and the patient’s subsequent treatment. We present an atypical case of right hallux herpetic whitlow with delayed diagnosis and associated cellulitis. The patient was admitted after seeing multiple providers for a progressive right hallux infection that presented as a mixture of vesicular lesions and apparent cellulitis. His history was positive for biting his fingernails and toenails, and the lesions were noted to be honeycomb-like, with minimal drainage. The lesions were then deroofed and viral cultures were obtained, which were positive for herpes simplex virus type 1, thus confirming a diagnosis of herpetic whitlow. Although he remained afebrile with negative wound cultures during admission, a secondary bacterial infection could not be excluded because of his nail avulsion and surrounding cellulitis. He was discharged on oral antibiotics, antivirals, and wound care recommendations. Herpetic whitlow should be included in the differential diagnosis of pedal digital lesions that appear as vesicular or cellulitic in the pediatric population. Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Clinicopathologic Characterization of Kaposi Sarcoma on the Foot and Ankle: Analysis of 11 Patients Seen in Our Clinics / Xingpei Hao in Journal of the American Podiatric Medical Association, vol 113, 06 (Novembre 2023)
[article]
in Journal of the American Podiatric Medical Association > vol 113, 06 (Novembre 2023)
Titre : Clinicopathologic Characterization of Kaposi Sarcoma on the Foot and Ankle: Analysis of 11 Patients Seen in Our Clinics Type de document : article de périodique Auteurs : Xingpei Hao ; Seth Rubenstein ; Joon Yim ; Erin Robles-Sherman ; Lee Firestone ; Alvin Bannerjee ; David Vieweger ; Elizabeth Daughtry ; Michelle Le ; Gene Mirkin Année de publication : 2023 Langues : Anglais (eng) Descripteurs (mots clés) : [Thésaurus HELB]:Paramédical:VIH
[Thésaurus Mesh]:S:Sarcome de Kaposi:Sarcome de Kaposi / physiopathologie
[Thésaurus Mesh]Cheville
[Thésaurus Mesh]Immunité
[Thésaurus Mesh]Pied
[Thésaurus Mesh]Sarcome de Kaposi
[Thésaurus Mesh]ThérapeutiqueRésumé : Background: Kaposi sarcoma (KS) has multiple clinical variants, and most frequently presents on the lower extremities. Anti–human immunodeficiency virus (HIV) therapy has significantly reduced the incidence of KS. However, KS is still prevalent in both HIV-infected and HIV-uninfected patients. This case series analysis aims to reveal the clinical presentations, differential diagnosis, and treatment options of KS on the foot and ankle.
Methods: Eleven cases of KS involving the foot and ankle were retrieved from our patient database, and their clinicopathologic features were analyzed.
Results: All patients were men, aged 29 to 85 years. Two types of KS were found: classic and acquired immunodeficiency syndrome–associated epidemic. The average ages of classic and epidemic KS were 65.7 and 41.8 years, respectively. Clinically, three patients manifested multiple erythematous or deep violaceous, or blue-violaceous macules on either the dorsal or plantar surfaces of both feet. Eight patients showed exophytic, pyogenic granuloma-like nodules on the plantar surface, heels, and toes. Histologically, all KSs had uniform intervening fascicles of elongated spindle cells with slit-like vascular spaces filled with red blood cells and immunoreactivity with human herpesvirus-8. The patients were treated according to HIV infection status. Human immunodeficiency virus–infected patients were treated with anti-HIV therapy after primary surgical excision or biopsy. Human immunodeficiency virus–negative patients were treated with either surgical excision, Mohs surgery, or a combination of surgical excision and local radiotherapy according to individual patient clinical presentation.
Conclusions: Kaposi sarcoma is still prevalent in both HIV-infected and HIV-uninfected patients with a variety of clinical presentations. Biopsy, with histologic evaluation, in combination with immunohistochemistry is essential for the differential diagnosis. The patient should be treated according their clinical manifestation, staging, comorbidity, and immune function.
Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Periungual Amelanocytic Malignant Melanoma with Osteocartilaginous Differentiation of the Right Hallux / Enzo Leone in Journal of the American Podiatric Medical Association, vol. 113, 01 (Janvier 2023)
[article]
in Journal of the American Podiatric Medical Association > vol. 113, 01 (Janvier 2023)
Titre : Periungual Amelanocytic Malignant Melanoma with Osteocartilaginous Differentiation of the Right Hallux Type de document : article de périodique Auteurs : Enzo Leone ; Gene Mirkin ; Xingpei Hao Année de publication : 2023 Langues : Anglais (eng) Descripteurs (mots clés) : [Thésaurus HELB]:Paramédical:Chirurgie
[Thésaurus Mesh]Hallux
[Thésaurus Mesh]Mélanocytes
[Thésaurus Mesh]Mélanome
[Thésaurus Mesh]Ongle incarnéMots-clés : mélanome malin à différenciation ostéocartilagineuse Résumé : Malignant melanoma with osteocartilaginous differentiation is extremely rare. We report a case of periungual osteocartilaginous melanoma (OCM) on the right hallux. A 59-year-old man presented with a rapidly growing mass with drainage on his right great toe after treatment of ingrown toenail and infection 3 months earlier. Physical examination showed a 2.0 1.5 1.0-cm, malodorous, erythematous, dusky, granuloma-like mass along the fibular border of the right hallux. Pathologic evaluation of the excisional biopsy revealed diffuse epithelioid and chondroblastoma-like melanocytes with atypia and pleomorphism in the dermis with strong SOX10 immunostaining. The lesion was diagnosed as osteocartilaginous melanoma. The patient was referred to a surgical oncologist for further treatment. Osteocartilaginous melanoma is a rare variant of malignant melanoma that needs to be differentiated from chondroblastoma and other lesions. Immunostains for SOX10, H3K36M, and SATB2 are helpful for the differential diagnosis. Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type on the Dorsal Foot in a Senior Woman A Case Report / Joel Kelly in Journal of the American Podiatric Medical Association, vol. 112, 06 (Novembre 2022)
[article]
in Journal of the American Podiatric Medical Association > vol. 112, 06 (Novembre 2022)
Titre : Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type on the Dorsal Foot in a Senior Woman A Case Report Type de document : article de périodique Auteurs : Joel Kelly ; Gene Mirkin ; Joon Yim ; Xingpei Hao Année de publication : 2022 Langues : Anglais (eng) Descripteurs (mots clés) : [Thésaurus Mesh]Lymphomes
[Thésaurus Mesh]Membre inférieur
[Thésaurus Mesh]Pied
[Thésaurus Mesh]Tumeurs
[Thésaurus HELB]:Paramédical:Cas cliniqueMots-clés : Lymphome cutané diffus primaire à grandes cellules B Résumé : Primary cutaneous diffuse large B-cell lymphoma, leg type (PCDLBCL-LT) is a rare variant of the cutaneous B-cell lymphomas, with rapid growth and poor prognosis. Here, we report a case of PCDLBCL-LT on the foot in a senior woman. An 81-year-old woman presented with a rapidly growing mass on her left foot, and discoloration in both lower legs over the past 2 months was analyzed. Physical examination revealed hyperpigmented macules and papules on both lower extremities and a 3.0 2.0 0.5-cm, gray-dark nodule on the dorsal surface of the left foot. Histologic observation of the punch biopsy specimen revealed a sheet of atypical large centroblast/immunoblast-like lymphocytes; diffusely and evenly distributed in the dermis; with the immunophenotypes of CD45-positive, CD20-positive, Melan A-negative, Sox10-negative, S-100–negative, and CK20-negative; and a very high Ki-67 proliferative index (.90%). Further punch biopsy specimens of papules in the patient’s lower extremities and bone marrow did not reveal atypical lymphoid tissues. Positron emission tomography/ computed tomography did not show any metastatic lesions in distant organs and lymph nodes. The lesion was diagnosed as PCDLBCL-LT stage T1N0M0. The patient was treated with four cycles of combined therapy of rituximab and cyclophosphamide, hydroxydaunorubicin, vincristine (Oncovin), and prednisolone and the tumor was further treated with local radiotherapy. The tumor size was significantly shrunken. Primary cutaneous diffuse large Bcell lymphoma, leg type is a rare entity on the foot, characterized by a confluent sheet of diffuse large centroblast- and or immunoblast-like B cells with B-cell immunophenotyping. The combined therapy of rituximab and cyclophosphamide, hydroxydaunorubicin, vincristine (Oncovin), and prednisolone is the first-line treatment regimen, with increased survival. Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Soft-Tissue Chondroma in the Right Hallux: A Case Report / Xingpei Hao in Journal of the American Podiatric Medical Association, vol. 109,06 (Novembre-décembre 2019)
[article]
in Journal of the American Podiatric Medical Association > vol. 109,06 (Novembre-décembre 2019)
Titre : Soft-Tissue Chondroma in the Right Hallux: A Case Report Type de document : article de périodique Auteurs : Xingpei Hao ; Joon Yim ; Chenfeng Qi ; Gene Mirkin Année de publication : 2019 Langues : Anglais (eng) Descripteurs (mots clés) : [Thésaurus Mesh]Chondrome
[Thésaurus Mesh]Hallux
[Thésaurus Mesh]Présentations de casRésumé : Soft-tissue chondroma is a rare, benign tumor. It is predominantly found in the hands and feet, but rarely in the toes. In this article, we report a digital soft-tissue chondroma that presented as a painful nodule of 5 years' duration in a 67-year-old man. Physical examination revealed a round, solid, movable nodule measuring 7 mm in diameter. Radiographs showed faint linear calcifications in the nodule under the right hallux proximal phalanx neck. The mass was completely excised, and pathologic observation revealed a mass composed of mature chondrocytes in a cartilaginous matrix, consistent with a chondroma. Even though this is a benign tumor, it needs to be differentiated from other tumors, including schwannoma, leiomyoma, chondrosarcoma, and others. Surgical excision is the preferred treatment. Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Subungual Exostosis on the Right Hallux / Michael Tritto in Journal of the American Podiatric Medical Association, vol. 111, 06 (Novembre-décembre 2021)
PermalinkA Subungual Nevoid Melanoma of the Right Hallux from a 65-Year-Old Man A Case Report / Mark Quist in Journal of the American Podiatric Medical Association, vol. 113, 04 (Juillet 2023)
PermalinkThe Pedal Subcutaneous Phaeohyphomycotic Cyst in an Immunocompetent Adult Man A Case Report / Mo Esmaili in Journal of the American Podiatric Medical Association, vol. 112, 04 (Juillet 2022)
Permalink