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Détail de l'auteur
Auteur Lidia RemolÃ-Sargues
Documents disponibles écrits par cet auteur
Ajouter le résultat dans votre panier Affiner la rechercheCase Report: Optic Nerve Atrophy Secondary to Sjögren Syndrome / Lidia RemolÃ-Sargues in OVS : Optometry & Vision Science, vol. 99, 10 (octobre 2022)
[article]
in OVS : Optometry & Vision Science > vol. 99, 10 (octobre 2022)
Titre : Case Report: Optic Nerve Atrophy Secondary to Sjögren Syndrome Type de document : article de périodique Auteurs : Lidia RemolÃ-Sargues ; Carolina GarcÃa-Villanueva ; Clara Monferrer-Adsuara ; Alicia Garcia ; Belén López-Salvador ; Enrique Cervera-Taulet Année de publication : 2022 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]Atteintes du nerf optique
[Thésaurus Mesh]Diagnostic
[Thésaurus Mesh]Syndrome de Gougerot-SjögrenMots-clés : Atrophie Résumé : SIGNIFICANCE: Acute syphilitic posterior placoid chorioretinitis (ASPPC) is a rare clinical presentation of ocular syphilis. The worldwide incidence of syphilis has recently increased. Clinicians should be familiar with the distinct appearance and imaging findings of ASPPC and promptly initiate antibiotic treatment to limit functional vision loss and systemic complications of neurosyphilis. PURPOSE: This case demonstrates the utility of optical coherence tomography angiography (OCT-A) imaging to further understand the pathophysiology and visual prognosis of ASPPC. CASE REPORT: A 75-year-old man presented with 7 days of decreased vision in his left eye. His visual acuity was 20/20 in the right eye and 20/200 in the left eye. Fundus examination revealed placoid lesions in the superior and inferotemporal aspects of the posterior pole in the right eye and a large placoid macular lesion in the left eye. Optical coherence tomography imaging revealed disruption and loss of the ellipsoid zone and external limiting membrane, nodular elevations on the retinal pigment epithelium, and choroidal hyperreflective punctate lesions in the left eye. Optical coherence tomography angiography displayed choriocapillaris perfusion flow voids greater in the left eye than in the right eye. Two months after penicillin treatment, the placoid lesions resolved in both eyes with an improvement in outer retinal structural abnormalities on optical coherence tomography imaging and visual acuity to 20/25 in the left eye. Eleven months after presentation, the OCT-A choriocapillaris flow voids had improved without complete restoration. Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Ipilimumab-induced Multisystem Autoimmune-like Toxicities Suggestive of Vogt-Koyanagi-Harada–like Syndrome / Clara Monferrer-Adsuara in OVS : Optometry & Vision Science, vol. 98, 11 (Novembre 2021)
[article]
in OVS : Optometry & Vision Science > vol. 98, 11 (Novembre 2021)
Titre : Ipilimumab-induced Multisystem Autoimmune-like Toxicities Suggestive of Vogt-Koyanagi-Harada–like Syndrome Type de document : article de périodique Auteurs : Clara Monferrer-Adsuara ; Laura Hernández-Bel ; MarÃa Luisa Hernández-Garfella ; Lidia RemolÃ-Sargues ; Miguel Ortiz-Salvador ; Verónica Castro-Navarro ; Enrique Cervera-Taulet Année de publication : 2021 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]Auto-immunité
[Thésaurus Mesh]Effets secondaires indésirables des médicaments
[Thésaurus Mesh]Syndrome uvéo-méningo-encéphalique
[Thésaurus Mesh]Traitement médicamenteux
[Thésaurus Mesh]Uvéite
[Thésaurus HELB]:Paramédical:IpilimumabMots-clés : syndrome de Vogt-Koyanagi-Harada Résumé : SIGNIFICANCE
The emergence of new cancer therapies has dramatically improved outcomes in metastatic melanoma. Immune checkpoint inhibitors have been the most effective treatment. Although, as a direct consequence of the immune dysregulation induced by them, adverse effects termed immune-related adverse events are observed in more than 60% of the patients.
PURPOSE
We describe the clinical presentation of Vogt-Koyanagi-Harada–like syndrome in a patient with concomitant systemic melanoma treatment with ipilimumab, a cytotoxic T lymphocyte–associated antigen 4 blocker.
METHODS
This study aimed to report a case of ipilimumab-induced vitritis, papillitis, and skin and auditory signs suggestive of Vogt-Koyanagi-Harada–like syndrome.
CASE REPORT
A 64-year-old woman with metastatic melanoma presented with bilateral blurred vision and hearing loss upon completion of three cycles of treatment with ipilimumab. Ophthalmologic examination revealed a bilateral granulomatous uveitis with intense vitritis and papillitis. The result of optical coherence tomography was normal, and fluorescein angiography confirmed the bilateral papillary edema. Ipilimumab was withdrawn, and treatment with oral and systemic steroids led to a rapid improvement in the ophthalmologic and auditory manifestations. Three months after initial presentation, the patient developed vitiligo and poliosis.
CONCLUSIONS
Vogt-Koyanagi-Harada–like syndrome can develop in the process of immunological deregulation by ipilimumab in the treatment of metastatic melanoma and can correlate temporally with the efficacy of the drug in tumor regression. These observations may help elucidate the underlying mechanism of Vogt-Koyanagi-Harada syndrome as well as the relation between tumor-associated tolerance and autoimmunity.Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Multimodal Imaging Features of an ABCA4 Cone Dystrophy / Clara Monferrer-Adsuara in OVS : Optometry & Vision Science, vol. 99, 02 (février 2022)
[article]
in OVS : Optometry & Vision Science > vol. 99, 02 (février 2022)
Titre : Multimodal Imaging Features of an ABCA4 Cone Dystrophy Type de document : article de périodique Auteurs : Clara Monferrer-Adsuara ; Javier Montero-Hernández ; Verónica Castro-Navarro ; Lidia RemolÃ-Sargues ; Enrique Cervera-Taulet Année de publication : 2022 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]:D:Diagnostic par imagerie:Diagnostic par imagerie / classification
[Thésaurus Mesh]Dépistage visuel
[Thésaurus Mesh]Maladies de l'oeil
[Thésaurus Mesh]Maladies génétiques congénitalesMots-clés : dystrophies des cônes dystrophies des cônes et des bâtonnets Résumé : SIGNIFICANCE
Cone dystrophies and cone-rod dystrophies are a group of rare inherited pathologies characterized by degeneration of cone photoreceptors and subsequent rod involvement. The identification of causative genes is essential for diagnosis, and advanced imaging is acquiring great value in the characterization of the different phenotypic expressions.
PURPOSE
We describe genotype-phenotype associations of an autosomal recessive ABCA4-associated cone dystrophy using multimodal imaging.
CASE REPORT
A 34-year-old woman presented with progressive visual acuity decay. Visual acuity was 20/32 for her right eye and 20/25 for her left eye. A central scotoma was detected on a 10-2 Humphrey visual field in both eyes. Funduscopy revealed perifoveal retinal pigment epithelial changes, and fundus autofluorescence using blue excitation light showed decreased autofluorescence in the central fovea of both eyes with surrounding annular ring of increased autofluorescence in the perifoveal zone; green excitation light fundus autofluorescence was more accurate in the characterization of the size, perimeter, and circularity of central hypofluorescent lesions. Optical coherence tomography revealed an incomplete focal cavitation in both foveas, and optical coherence tomography angiography images showed a reduction in the superficial and deep capillary plexus density, an increased foveal avascular area, and subtle voids in choriocapillaris blood flow. Electroretinography was consistent with cone dystrophy, and molecular testing revealed the alteration of the ABCA4 gene.
CONCLUSIONS
The identification of an incomplete focal cavitation could alert the clinician to consider early ABCA4 central cone dystrophy. The patient in this case also exhibited reduced vessel density in the foveal area. Both of these characteristics could be important features related to the underlying genetic mutation.Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Nutritional and Toxic Optic Neuropathy: A Diagnostic Dilemma : Case Report / Clara Monferrer-Adsuara in OVS : Optometry & Vision Science, vol. 97, 07 (Juillet 2020)
[article]
in OVS : Optometry & Vision Science > vol. 97, 07 (Juillet 2020)
Titre : Nutritional and Toxic Optic Neuropathy: A Diagnostic Dilemma : Case Report Type de document : article de périodique Auteurs : Clara Monferrer-Adsuara ; Carolina GarcÃa-Villanueva ; LucÃa Mata-Moret ; Miguel Ortiz-Salvador ; Lidia RemolÃ-Sargues ; Enrique Cervera-Taulet Année de publication : 2020 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]Atteintes du nerf optique
[Thésaurus Mesh]Maladies de carence
[Thésaurus Mesh]Régime alimentaire
[Thésaurus Mesh]Toxines biologiques
[Thésaurus Mesh]Vision oculaire
[Thésaurus Type de publication]Présentations de casRésumé : SIGNIFICANCE
Nutritional and toxic optic neuropathies are rare disorders characterized by visual impairment due to optic nerve damage by a toxin, usually with coexisting nutritional deficiencies. Its pathophysiology is still unclear, and multiple mechanisms implicated act synergistically to bring about this condition. The decline in its incidence and its confusing clinical appearance make diagnosing nutritional and toxic optic neuropathies challenging.
PURPOSE
This is an observational clinical case report of an atypical clinical case of a nutritional and toxic optic neuropathy with a subacute presentation and papilledema at the time of diagnosis. The patient provided written informed consent for medical information and images to be published.
CASE REPORT
A 47-year-old man presented with progressive, painless bilateral decrease in central vision over 15 days. The patient had a long-standing history of alcohol abuse and was a heavy smoker. The examination revealed dyschromatopsia, 20/400 visual acuity on both eyes, and no relative afferent pupillary defect. Funduscopy revealed bilateral papilledema. A visual field test showed generalized depression with centrocecal involvement in the left eye. Laboratory studies evidenced decreased vitamin B 12 /B 1 and red blood cell folate levels, increased acute phase reactants, hypertransaminasemia, and macrocytic anemia. Serologies and methanol in urine were negative. After the discontinuation of tobacco use and alcohol accompanied by vitamin supplementation, our patient's visual field, visual acuity, and papilledema improved remarkably. After 5 months, visual acuity and funduscopy were normal.
CONCLUSIONS
Although some hallmark signs were visible in this case, its subacute presentation and the presence of papilledema at diagnosis caused some diagnostic uncertainty. Nutritional and toxic optic neuropathy is a rare and challenging diagnosis because of a lack of biomarkers. Eye care clinicians should consider nutritional and toxic optic neuropathies to prevent severe and irreversible visual damage resulting from underdiagnosis and mismanagement.Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Quantitative Assessment of Retinal and Choroidal Microvasculature in Asymptomatic Patients with Carotid Artery Stenosis / Clara Monferrer-Adsuara in OVS : Optometry & Vision Science, vol. 100, 11 (Novembre 2023)
[article]
in OVS : Optometry & Vision Science > vol. 100, 11 (Novembre 2023)
Titre : Quantitative Assessment of Retinal and Choroidal Microvasculature in Asymptomatic Patients with Carotid Artery Stenosis Type de document : article de périodique Auteurs : Clara Monferrer-Adsuara ; Lidia RemolÃ-Sargues ; Catalina Navarro-Palop ; Enrique Cervera-Taulet ; Javier Montero-Hernández ; Pascual Medina-Bessó ; Verónica Castro-Navarro Année de publication : 2023 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus HELB]:Paramédical:Angiographie par tomodensitométrie
[Thésaurus HELB]:Paramédical:Dépistage
[Thésaurus Mesh]Accident vasculaire cérébral
[Thésaurus Mesh]Choroïde
[Thésaurus Mesh]Études d'évaluation comme sujetMots-clés : maladie carotidienne sténose de l'artère carotide modifications microvasculaires choroïdiennes microvascularisation rétinienne Résumé : SIGNIFICANCE: Carotid disease contributes to 15 to 20% of all ischemic strokes, one of the leading causes of permanent disabilities and mortality globally. With its growing prevalence and the inflicted disability rates, screening for anomalies that precede the onset of its serious complications is of crucial global significance. PURPOSE: This study aimed to assess the relationship between retinal and choroidal perfusion changes with the degree of stenosis using quantitative swept-source optical coherence tomography angiography in patients with internal carotid artery stenosis. METHODS: A retrospective cohort study was conducted in 72 eyes with carotid stenosis. According to the degree of stenosis, the participants were divided into a healthy group (group 1: 34 eyes), a mild-moderate stenosis group (group 2: 22 eyes), and a severe stenosis group (group 3: 16 eyes). Swept-source optical coherence tomography angiography was performed to scan macular fovea. Capillary density values in the different retinal and choroidal layers were the major measurements for our study. RESULTS: Mean vessel density in the midchoroid layer was significantly higher in groups 2 and 3 compared with group 1. Deep choroid disclosed significantly superior vascular density values in group 3 compared with groups 2 and 1. Superficial and deep capillary plexus showed decreased vascular density values when comparing group 3 with groups 1 and 2, although they were not significant. CONCLUSIONS: Our report provides the first evidence that choroidal microvascular changes were correlated with severity of carotid artery stenosis. Optical coherence tomography angiography can sensitively detect subtle, early changes in the ocular blood in carotid disease representing a useful, noninvasive, and objective approach to the retinal microvasculature. Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire