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> S > Syndrome de nécrose rétinienne aigüe
Syndrome de nécrose rétinienne aigüe
Mild to fulminant necrotizing vaso-occlusive retinitis associated with a high incidence of retinal detachment and poor vision outcome.
Synonyme(s)
Nécrose aiguë de la rétine; Nécrose aigüe de la rétine; Nécrose rétinienne aiguë; Nécrose rétinienne aigüeRelation(s)
- voir aussi au terme générique : [Descripteurs (mots clés)] Rétinite
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Case Report: Acute Retinal Necrosis after Intravitreal Ranibizumab for Exudative Macular Degeneration / Ying Pan in OVS : Optometry & Vision Science, vol. 98, 03 (Mars 2021)
[article]
in OVS : Optometry & Vision Science > vol. 98, 03 (Mars 2021)
Titre : Case Report: Acute Retinal Necrosis after Intravitreal Ranibizumab for Exudative Macular Degeneration Type de document : article de périodique Auteurs : Ying Pan ; Xiaoli Huang ; Zhifeng Wu ; Shui Lu ; Tiantian Chen ; Wenjun Zou Année de publication : 2021 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]:S:Syndrome de nécrose rétinienne aigüe:Syndrome de nécrose rétinienne aigüe / étiologie
[Thésaurus Mesh]Atteintes du nerf optique
[Thésaurus Mesh]Dégénérescence maculaire
[Thésaurus Mesh]Effets secondaires indésirables des médicaments
[Thésaurus Mesh]Syndrome de nécrose rétinienne aigüeMots-clés : ranibizumab traitement antiviral Résumé : SIGNIFICANCE: Acute retinal necrosis (ARN) may occur after intravitreal ranibizumab (IVR) treatment for patients
with exudative age-related macular degeneration (AMD). Awareness of this unusual but devastating complication
after IVR is needed. Early identification may help provide timely antiviral treatment and prevent irreversible visual loss.
PURPOSE: This study aimed to report a case of ARN after IVR in a patient with exudative AMD.
CASE REPORT: A 67-year-old male patient complained of blurred vision in his left eye for 1 month. The patient was
diagnosed with exudative AMD after detailed ophthalmic clinical evaluations. He received IVR once in his left eye.
Three days after IVR, he developed varicella-zoster virus–associated ARN, which was treated with systemic and intravitreal antiviral therapy. Because of progressive inflammation, the patient underwent 25G pars plana vitrectomy
with silicone oil tamponade. Seven months later, the patient was administered intravitreal aflibercept once in his
left eye. Three months after intravitreal aflibercept, he underwent removal of silicone oil, and retinal detachment
occurred 2 weeks after the surgery because of low IOP, and the patient eventually discontinued treatment.
CONCLUSIONS: This study reports the first case of varicella-zoster virus–associated ARN after IVR. Early ARN may
be very difficult to distinguish from intraocular inflammation after IVR. Therefore, early detection of viral DNA in
the intraocular fluid using polymerase chain reaction is recommended. Immediate antiviral treatment may be beneficial to prevent severe visual loss.Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Case report: varicella-zoster encephalitis with acute retinal necrosis and oculomotor nerve palsy / Steven Charles Quan in OVS : Optometry & Vision Science, vol. 96, 05 (Mai 2019)
[article]
in OVS : Optometry & Vision Science > vol. 96, 05 (Mai 2019)
Titre : Case report: varicella-zoster encephalitis with acute retinal necrosis and oculomotor nerve palsy Type de document : article de périodique Auteurs : Steven Charles Quan ; Dimitra Skondra Année de publication : 2019 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus HELB]:Optique:Perte de vision
[Thésaurus HELB]:Paramédical:Prévention
[Thésaurus Mesh]:E:Encéphalite zostérienne:Encéphalite zostérienne / complications
[Thésaurus Mesh]:S:Syndrome de nécrose rétinienne aigüe:Syndrome de nécrose rétinienne aigüe / thérapie
[Thésaurus Mesh]Syndrome de nécrose rétinienne aigüeRésumé : SIGNIFICANCE Varicella-zoster virus is a common cause of morbidity and vision loss in patients worldwide. It can affect any structure of the eye, from keratitis to acute retinal necrosis. Rapid diagnosis and treatment significantly improve clinical outcomes and quality of life.
PURPOSE The purpose of this study was to demonstrate a case where urgent referral to the emergency department was required to treat a patient with disseminated herpes zoster infection.
CASE REPORT This is a rare case of varicella-zoster virus encephalitis in a 70-year-old immunocompetent white man who initially presented to the eye clinic for vertical diplopia and floaters. He also had prior thoracic dermatomal rash, followed by new-onset headaches and cerebellar ataxia. Examination revealed a partial oculomotor nerve palsy in the right eye with bilateral optic disc edema and areas of retinitis consistent with acute retinal necrosis in both eyes. Polymerase chain reaction analysis of his aqueous humor and cerebrospinal fluid confirmed an active zoster infection. He received combination systemic and intravitreal antiviral medication until his retinitis resolved but required adjustments for recalcitrant disease and drug-induced nephrotoxicity. While on maintenance dosing of oral valacyclovir, he experienced reactivation in the form of bilateral vasculitis, which was successfully managed once restarting therapeutic oral dosing.
CONCLUSIONS This case describes a successful clinical course of acute retinal necrosis with strategies for its treatment in the setting of varicella-zoster encephalitis. Antiviral medication should be given as soon as possible, as prompt treatment has been shown to improve patient outcomes, although prognosis is typically poor in these cases. Multiple specialists are often needed to address different clinical challenges, including central nervous system involvement, viral strain resistance, disease reactivation, and drug toxicity.Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire