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Auteur Krista R. Kelly
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Ajouter le résultat dans votre panier Affiner la rechercheBaseline and Clinical Factors Associated with Response to Amblyopia Treatment in a Randomized Clinical Trial / Eileen E. Birch in OVS : Optometry & Vision Science, vol. 97, 05 (Mai 2020)
[article]
in OVS : Optometry & Vision Science > vol. 97, 05 (Mai 2020) . - p. 316-323
Titre : Baseline and Clinical Factors Associated with Response to Amblyopia Treatment in a Randomized Clinical Trial Type de document : article de périodique Auteurs : Eileen E. Birch ; Reed M. Jost ; Krista R. Kelly ; Joel N. Leffler ; Lori Dao ; Cynthia L. Beauchamp Année de publication : 2020 Article en page(s) : p. 316-323 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]:A:Amblyopie:Amblyopie / thérapie
[Thésaurus Mesh]Amblyopie
[Thésaurus Mesh]Enfant
[Thésaurus Mesh]Essais contrôlés randomisés comme sujet
[Thésaurus Mesh]Résultat thérapeutiqueMots-clés : amblyopia therapeutics randomized controlled trials as topic treatment outcome child Résumé : SIGNIFICANCE: We sought to identify baseline and clinical factors that were predictive of the response to amblyopia treatment. We report that binocular amblyopia treatment may be especially effective for moderate amblyopia in orthotropic children. PURPOSE: We previously reported results from the primary cohort (n = 28) enrolled in a randomized clinical trial (NCT02365090), which found that binocular amblyopia treatment was more effective than patching. Enrollment of an additional 20 children was pre-planned to provide the opportunity to examine factors that may be predictive of response to amblyopia treatment. METHODS: Forty-eight children (4 to 10 years old) were enrolled, with 24 randomized to contrast-rebalanced binocular game treatment (1 hour a day, 5 days a week) and 24 to patching treatment (2 hours a day, 7 days a week). The primary outcome was change in amblyopic eye best-corrected visual acuity at the 2-week visit. Baseline factors examined were age at enrollment, visual acuity, stereoacuity, and suppression. Clinical factors were etiology, age at diagnosis, prior treatment, and ocular alignment. RESULTS: At 2 weeks, visual acuity improvement was significantly greater with the binocular game than patching. Children with moderate amblyopia and orthotropia had more visual acuity improvement with binocular game play than did those with severe amblyopia. In addition, children who spent more time playing the binocular game had more improvement. We were not able to confidently identify any baseline or clinical factors that were associated with response to patching treatment. CONCLUSIONS: Binocular amblyopia treatment was more effective among orthotropic children with moderate amblyopia than among children with microtropia or severe amblyopia. Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire A Randomized Trial of Binocular Dig Rush Game Treatment for Amblyopia in Children Aged 4 to 6 Years / Ruth E. Manny in OVS : Optometry & Vision Science, vol.99, 03 (Mars 2022)
[article]
in OVS : Optometry & Vision Science > vol.99, 03 (Mars 2022)
Titre : A Randomized Trial of Binocular Dig Rush Game Treatment for Amblyopia in Children Aged 4 to 6 Years Type de document : article de périodique Auteurs : Ruth E. Manny ; Jonathan M. Holmes ; Raymond T. Kraker ; Zhuokai Li ; Amy L. Waters ; Krista R. Kelly ; Lingkun Kong ; [et al.] Année de publication : 2022 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]:A:Amblyopie:Amblyopie / thérapie
[Thésaurus Mesh]Acuité visuelle
[Thésaurus Mesh]Enfant
[Thésaurus Mesh]Essais contrôlés randomisés comme sujet
[Thésaurus Mesh]Lentilles de contactRésumé : SIGNIFICANCE: Binocular treatment for unilateral amblyopia is an emerging treatment that requires evaluation
through a randomized clinical trial.
PURPOSE: This study aimed to compare change in amblyopic-eye visual acuity (VA) in children aged 4 to 6 years
treated with the dichoptic binocular iPad (Apple, Cupertino, CA) game, Dig Rush (not yet commercially available;
Ubisoft, Montreal, Canada), plus continued spectacle correction versus continued spectacle correction alone.
METHODS: Children (mean age, 5.7 years) were randomly assigned to home treatment for 8 weeks with the iPad
game (prescribed 1 h/d, 5 d/wk [n = 92], or continued spectacle correction alone [n = 90]) in a multicenter randomized clinical trial. Before enrollment, children wearing spectacles were required to have at least 16 weeks of wear or
no improvement in amblyopic-eye VA (<0.1 logMAR) for at least 8 weeks. Outcome was change in amblyopic-eye
VA from baseline to 4 weeks (primary) and 8 weeks (secondary) assessed by masked examiner.
RESULTS: A total of 182 children with anisometropic (63%), strabismic (16%; <5Δ near, simultaneous prism and
cover test), or combined-mechanism (20%) amblyopia (20/40 to 20/200; mean, 20/63) were enrolled. After
4 weeks, mean amblyopic VA improved by 1.1 logMAR lines with binocular treatment and 0.6 logMAR lines with
spectacles alone (adjusted difference, 0.5 lines; 95.1% confidence interval [CI], 0.1 to 0.9). After 8 weeks, results
(binocular treatment: mean amblyopic-eye VA improvement, 1.3 vs. 1.0 logMAR lines with spectacles alone; adjusted difference, 0.3 lines; 98.4% CI, −0.2 to 0.8 lines) were inconclusive because the CI included both zero and
the pre-defined difference in mean VA change of 0.75 logMAR lines.
CONCLUSIONS: In 4- to 6-year-old children with amblyopia, binocular Dig Rush treatment resulted in greater improvement in amblyopic-eye VA for 4 weeks but not 8 weeks. Future work is required to determine if modifications
to the contrast increment algorithm or other aspects of the game or its implementation could enhance the treatment effect.Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Slow Binocular Reading in Amblyopic Children Is a Fellow Eye Deficit / Krista R. Kelly in OVS : Optometry & Vision Science, vol. 100, 03 (Mars 2023)
[article]
in OVS : Optometry & Vision Science > vol. 100, 03 (Mars 2023)
Titre : Slow Binocular Reading in Amblyopic Children Is a Fellow Eye Deficit Type de document : article de périodique Auteurs : Krista R. Kelly ; Reed M. Jost ; Lindsey A. Hudgins ; David R. Stager ; Jeffrey S. Hunter ; Cynthia L. Beauchamp ; Lori Dao ; Eileen E. Birch Année de publication : 2023 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]Amblyopie
[Thésaurus Mesh]Enfant
[Thésaurus Mesh]Lecture
[Thésaurus Mesh]Troubles de l'apprentissage
[Thésaurus Mesh]Troubles de la vision
[Thésaurus Mesh]Vision binoculaireRésumé : SIGNIFICANCE: Amblyopic children read 25% slower than their peers during binocular silent reading. PURPOSE: We compared binocular reading to fellow eye reading to determine whether slow reading in amblyopic children is due to binocular inhibition; that is, the amblyopic eye is interfering during binocular reading. METHODS: In a cross-sectional study, 38 children with amblyopia and 36 age-similar control children who completed grades 1 to 6 were enrolled. Children silently read grade-appropriate paragraphs during binocular reading and fellow eye reading while wearing ReadAlyzer eye-tracking goggles (Compevo AB, Stockholm, Sweden). Reading rate, number of forward saccades, number of regressive saccades, and fixation duration were analyzed between groups and between viewing conditions. We also examined whether sensory factors (amblyopia severity, stereoacuity, suppression) were related to slow reading. RESULTS: For amblyopic children, binocular reading versus fellow eye reading did not differ for reading rate (176 ± 60 vs. 173 ± 53 words per minute, P = .69), number of forward saccades (104 ± 35 vs. 97 ± 33 saccades/100 words, P = .18), number of regressive saccades (21 ± 15 vs. 22 ± 13 saccades/100 words, P = .75), or fixation duration (0.31 ± 0.06 vs. 0.32 ± 0.07 seconds, P = .44). As expected, amblyopic children had a slower reading rate and more forward saccades than control children during binocular reading and fellow eye reading. Slow reading was not related to any sensory factors. CONCLUSIONS: Binocular reading did not differ from fellow eye reading in amblyopic children. Thus, binocular inhibition is unlikely to play a role in slow binocular reading and is instead a fellow eye deficit that emerges from a disruption in binocular visual experience during development. Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire