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Auteur Ruth E. Manny
Documents disponibles écrits par cet auteur
Ajouter le résultat dans votre panier Affiner la rechercheA Randomized Trial of Binocular Dig Rush Game Treatment for Amblyopia in Children Aged 4 to 6 Years / Ruth E. Manny in OVS : Optometry & Vision Science, vol.99, 03 (Mars 2022)
[article]
in OVS : Optometry & Vision Science > vol.99, 03 (Mars 2022)
Titre : A Randomized Trial of Binocular Dig Rush Game Treatment for Amblyopia in Children Aged 4 to 6 Years Type de document : article de périodique Auteurs : Ruth E. Manny ; Jonathan M. Holmes ; Raymond T. Kraker ; Zhuokai Li ; Amy L. Waters ; Krista R. Kelly ; Lingkun Kong ; [et al.] Année de publication : 2022 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]:A:Amblyopie:Amblyopie / thérapie
[Thésaurus Mesh]Acuité visuelle
[Thésaurus Mesh]Enfant
[Thésaurus Mesh]Essais contrôlés randomisés comme sujet
[Thésaurus Mesh]Lentilles de contactRésumé : SIGNIFICANCE: Binocular treatment for unilateral amblyopia is an emerging treatment that requires evaluation
through a randomized clinical trial.
PURPOSE: This study aimed to compare change in amblyopic-eye visual acuity (VA) in children aged 4 to 6 years
treated with the dichoptic binocular iPad (Apple, Cupertino, CA) game, Dig Rush (not yet commercially available;
Ubisoft, Montreal, Canada), plus continued spectacle correction versus continued spectacle correction alone.
METHODS: Children (mean age, 5.7 years) were randomly assigned to home treatment for 8 weeks with the iPad
game (prescribed 1 h/d, 5 d/wk [n = 92], or continued spectacle correction alone [n = 90]) in a multicenter randomized clinical trial. Before enrollment, children wearing spectacles were required to have at least 16 weeks of wear or
no improvement in amblyopic-eye VA (<0.1 logMAR) for at least 8 weeks. Outcome was change in amblyopic-eye
VA from baseline to 4 weeks (primary) and 8 weeks (secondary) assessed by masked examiner.
RESULTS: A total of 182 children with anisometropic (63%), strabismic (16%; <5Δ near, simultaneous prism and
cover test), or combined-mechanism (20%) amblyopia (20/40 to 20/200; mean, 20/63) were enrolled. After
4 weeks, mean amblyopic VA improved by 1.1 logMAR lines with binocular treatment and 0.6 logMAR lines with
spectacles alone (adjusted difference, 0.5 lines; 95.1% confidence interval [CI], 0.1 to 0.9). After 8 weeks, results
(binocular treatment: mean amblyopic-eye VA improvement, 1.3 vs. 1.0 logMAR lines with spectacles alone; adjusted difference, 0.3 lines; 98.4% CI, −0.2 to 0.8 lines) were inconclusive because the CI included both zero and
the pre-defined difference in mean VA change of 0.75 logMAR lines.
CONCLUSIONS: In 4- to 6-year-old children with amblyopia, binocular Dig Rush treatment resulted in greater improvement in amblyopic-eye VA for 4 weeks but not 8 weeks. Future work is required to determine if modifications
to the contrast increment algorithm or other aspects of the game or its implementation could enhance the treatment effect.Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire A Randomized Trial of Objective Spectacle Prescriptions for Adults with Down Syndrome: Baseline Data and Methods / Heather Anderson in OVS : Optometry & Vision Science, vol. 98, 01 (Janvier 2021)
[article]
in OVS : Optometry & Vision Science > vol. 98, 01 (Janvier 2021)
Titre : A Randomized Trial of Objective Spectacle Prescriptions for Adults with Down Syndrome: Baseline Data and Methods Type de document : article de périodique Auteurs : Heather Anderson ; Julia Benoit ; Jason Marsack ; Ruth E. Manny ; Ayeswarya Ravikumar ; Karen D. Fern ; Kelsey R. Trast Année de publication : 2021 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]Calculs
[Thésaurus Mesh]Dépistage visuel
[Thésaurus Mesh]Lunettes correctrices
[Thésaurus Mesh]Syndrome de Down
[Thésaurus Mesh]Troubles de la réfraction oculaire
[Thésaurus Mesh]Troubles de la visionRésumé : SIGNIFICANCE: It is difficult to determine the most efficacious refractive correction for individuals with Down syndrome using routine clinical techniques. New objective methods that optimize spectacle corrections for this population may reduce limitations on daily living by improving visual quality. PURPOSE: This article describes the methods and baseline characteristics of study participants in a National Eye Institute–sponsored clinical trial to evaluate objectively derived spectacle corrections in adults with Down syndrome. Intersession repeatability of the primary outcome measure (distance visual acuity) is also reported. METHODS: Adults with Down syndrome were enrolled into a nine-visit study to compare clinically derived spectacle corrections and two different objective spectacle corrections derived from wavefront aberration data. Spectacle corrections were randomized and dispensed for 2 months each. Distance visual acuity was measured with a BaileyLovie–style chart. Intersession repeatability of acuity was established by performing difference versus mean analysis from binocular acuity measures obtained through habitual corrections at visits 1 and 2. RESULTS: Thirty adults (mean ± standard deviation age, 29 ± 10 years) with a large range of refractive errors were enrolled. Presenting visual acuity at visit 1 was reduced (right eye, 0.47 ± 0.20 logMAR; left eye, 0.42 ± 0.17 logMAR). The mean difference between visits 1 and 2 was 0.02 ± 0.06 logMAR, with a coefficient of repeatability (1.96 within-subject standard deviation) of 0.12 logMAR. CONCLUSIONS: This study seeks to investigate new strategies to determine optical corrections that may reduce commonly observed visual deficits in individuals with Down syndrome. The good intersession repeatability of acuity found in this study (six letters) indicates that, despite the presenc Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Uncorrected Refractive Error and Distance Visual Acuity in Children Aged 6 to 14 Years / Robert N. Kleinstein in OVS : Optometry & Vision Science, vol. 98, 01 (Janvier 2021)
[article]
in OVS : Optometry & Vision Science > vol. 98, 01 (Janvier 2021)
Titre : Uncorrected Refractive Error and Distance Visual Acuity in Children Aged 6 to 14 Years Type de document : article de périodique Auteurs : Robert N. Kleinstein ; Donald Mutti ; Loraine T. Sinnott ; Lisa Jones-Jordan ; Susan A. Cotter ; Ruth E. Manny ; Daniel Twelker ; Karla Zadnik Année de publication : 2021 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]Acuité visuelle
[Thésaurus Mesh]Calculs
[Thésaurus Mesh]Enfant
[Thésaurus Mesh]Troubles de la réfraction oculaireMots-clés : erreur de réfraction autoréfracteur distance Résumé : SIGNIFICANCE: This study presents the relationship between distance visual acuity and a range of uncorrected refractive errors, a complex association that is fundamental to clinical eye care and the identification of children needing refractive correction. PURPOSE: This study aimed to analyze data from the Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error Study to describe the relationship between distance uncorrected refractive error and visual acuity in children. METHODS: Subjects were 2212 children (51.2% female) 6 to 14 years of age (mean ± standard deviation, 10.2 ± 2.1 years) participating in the Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error Study between 2000 and 2010. Uncorrected distance visual acuity was measured using a high-contrast projected logMAR chart. Cycloplegic refractive error was measured using the Grand Seiko WR-5100K autorefractor. The ability of logMAR acuity to detect various categories of refractive error was examined using receiver operating characteristic curves. RESULTS: Isoacuity curves show that increasing myopic spherical refractive errors, increasing astigmatic refractive errors, or a combination of both reduces distance visual acuity. Visual acuity was reduced by approximately 0.5 minutes of MAR per 0.30 to 0.40 D of spherical refractive error and by approximately 0.5 minutes of MAR per 0.60 to 0.90 D of astigmatism. Higher uncorrected hyperopic refractive error had little effect on distance visual acuity. Receiver operating characteristic curve analysis suggests that a logMAR distance acuity of 0.20 to 0.32 provides the best balance between sensitivity and specificity for detecting refractive errors other than hyperopia. Distance acuity alone was ineffective for detecting hyperopic refractive errors. CONCLUSIONS: Higher myopic and/or astigmatic refractive errors were associated with predictable reductions in uncorrected distance visual acuity. The reduction in acuity per diopter of cylindrical error was about half that for spherical myopic error. Although distance acuity may be a useful adjunct to the detection of myopic spherocylindrical refractive errors, accommodation presumably prevents acuity from assisting in the detection of hyperopia. Alternate procedures need to be used to detect hyperopia Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Visual Acuity Outcomes in a Randomized Trial of Wavefront Metric-optimized Refractions in Adults with Down Syndrome / Heather Anderson in OVS : Optometry & Vision Science, vol. 99, 01 (Janvier 2022)
[article]
in OVS : Optometry & Vision Science > vol. 99, 01 (Janvier 2022)
Titre : Visual Acuity Outcomes in a Randomized Trial of Wavefront Metric-optimized Refractions in Adults with Down Syndrome Type de document : article de périodique Auteurs : Heather Anderson ; Jason Marsack ; Julia Benoit ; Ruth E. Manny ; Karen D. Fern Année de publication : 2022 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]:T:Troubles de la vision:Troubles de la vision / thérapie
[Thésaurus Mesh]Acuité visuelle
[Thésaurus Mesh]Essais cliniques comme sujet
[Thésaurus Mesh]Optométrie
[Thésaurus Mesh]Réfraction oculaire
[Thésaurus Mesh]Syndrome de Down
[Thésaurus Mesh]Tests de visionRésumé : SIGNIFICANCE
This study reports visual acuity outcomes from a clinical trial investigating an objective refraction strategy that may provide a useful tool for practitioners needing additional strategies to identify refractive corrections for adults with intellectual disability.
PURPOSE
Determining refractions for individuals with Down syndrome is challenging because of the presence of elevated refractive error, optical aberrations, and cognitive impairment. This randomized clinical trial evaluated the performance of spectacle corrections determined using clinical techniques and objective refractions derived from wavefront aberration measures.
METHODS
Thirty adults with Down syndrome had a clinical refraction determined by a single expert examiner using pre-dilation and post-dilation techniques appropriate for this population. Objective refractions were determined from dilated wavefront aberration measures that were processed post-visit to identify refractions that optimized each of two image quality metrics: pupil fraction tessellated and visual Strehl ratio in the spatial domain. The three refractions were dispensed in random order and worn for 2 months each. The primary outcome measure, binocular visual acuity, was obtained by a masked examiner administering a distance logMAR acuity test. To compare treatment types, mean acuity was compared using a two-sided type 3 F test of the treatment effect in a linear mixed-effects regression model, where the final model included fixed effects for treatment, period (1, 2, or 3), and first-order carryover effects.
RESULTS
The 2-month estimated least square means in binocular visual acuity (logMAR) were 0.34 (95% confidence interval [CI], 0.25 to 0.39) for clinical refractions, 0.31 (95% CI, 0.25 to 0.36) for pupil fraction tesselated refractions, and 0.33 (95% CI, 0.27 to 0.38) for visual Strehl ratio refractions. No statistically significant treatment effect was observed (F = 1.10, P = .34).
CONCLUSIONS
Objective refractions derived from dilated wavefront aberration measures resulted in acuity similar to expert clinician-derived refractions, suggesting that the objective method may be a suitable alternative for patients with Down syndrome.Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire