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Baseline and Clinical Factors Associated with Response to Amblyopia Treatment in a Randomized Clinical Trial / Eileen E. Birch in OVS : Optometry & Vision Science, vol. 97, 05 (Mai 2020)
[article]
in OVS : Optometry & Vision Science > vol. 97, 05 (Mai 2020) . - p. 316-323
Titre : Baseline and Clinical Factors Associated with Response to Amblyopia Treatment in a Randomized Clinical Trial Type de document : article de périodique Auteurs : Eileen E. Birch ; Reed M. Jost ; Krista R. Kelly ; Joel N. Leffler ; Lori Dao ; Cynthia L. Beauchamp Année de publication : 2020 Article en page(s) : p. 316-323 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]:A:Amblyopie:Amblyopie / thérapie
[Thésaurus Mesh]Amblyopie
[Thésaurus Mesh]Enfant
[Thésaurus Mesh]Essais contrôlés randomisés comme sujet
[Thésaurus Mesh]Résultat thérapeutiqueMots-clés : amblyopia therapeutics randomized controlled trials as topic treatment outcome child Résumé : SIGNIFICANCE: We sought to identify baseline and clinical factors that were predictive of the response to amblyopia treatment. We report that binocular amblyopia treatment may be especially effective for moderate amblyopia in orthotropic children. PURPOSE: We previously reported results from the primary cohort (n = 28) enrolled in a randomized clinical trial (NCT02365090), which found that binocular amblyopia treatment was more effective than patching. Enrollment of an additional 20 children was pre-planned to provide the opportunity to examine factors that may be predictive of response to amblyopia treatment. METHODS: Forty-eight children (4 to 10 years old) were enrolled, with 24 randomized to contrast-rebalanced binocular game treatment (1 hour a day, 5 days a week) and 24 to patching treatment (2 hours a day, 7 days a week). The primary outcome was change in amblyopic eye best-corrected visual acuity at the 2-week visit. Baseline factors examined were age at enrollment, visual acuity, stereoacuity, and suppression. Clinical factors were etiology, age at diagnosis, prior treatment, and ocular alignment. RESULTS: At 2 weeks, visual acuity improvement was significantly greater with the binocular game than patching. Children with moderate amblyopia and orthotropia had more visual acuity improvement with binocular game play than did those with severe amblyopia. In addition, children who spent more time playing the binocular game had more improvement. We were not able to confidently identify any baseline or clinical factors that were associated with response to patching treatment. CONCLUSIONS: Binocular amblyopia treatment was more effective among orthotropic children with moderate amblyopia than among children with microtropia or severe amblyopia. Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Case study : amblyopia care : oculocutaneous albinism / Ralf Beuschel in Global contact, 74 (Septembre-décembre 2016)
[article]
in Global contact > 74 (Septembre-décembre 2016) . - p. 16-19
Titre : Case study : amblyopia care : oculocutaneous albinism Type de document : article de périodique Auteurs : Ralf Beuschel ; Margarita Todorova Année de publication : 2016 Article en page(s) : p. 16-19 Langues : Anglais (eng) Descripteurs (mots clés) : [Thésaurus Mesh]:A:Amblyopie:Amblyopie / thérapie
[Thésaurus Mesh]Albinisme oculocutané
[Thésaurus Mesh]Amblyopie
[Thésaurus Mesh]Lentilles de contact
[Thésaurus Mesh]Mélanines
[Thésaurus Mesh]Présentations de casRésumé : Oculocutaneous albinism refers to the form of albinism where not only the eyes but also the skin and hair are affected. The umbrella term albinism is derived from "albus" the latin word for white. In this case, there is a congenital pigment disorder in which too little melanin is produced. The incidence worldwide is 1:20,000 although in Africa it is even higher at 1:10,000. Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité G Périodique Erasme - périodiques Périodiques Disponible G Périodique Erasme - périodiques Périodiques Disponible A Randomized Trial of Binocular Dig Rush Game Treatment for Amblyopia in Children Aged 4 to 6 Years / Ruth E. Manny in OVS : Optometry & Vision Science, vol.99, 03 (Mars 2022)
[article]
in OVS : Optometry & Vision Science > vol.99, 03 (Mars 2022)
Titre : A Randomized Trial of Binocular Dig Rush Game Treatment for Amblyopia in Children Aged 4 to 6 Years Type de document : article de périodique Auteurs : Ruth E. Manny ; Jonathan M. Holmes ; Raymond T. Kraker ; Zhuokai Li ; Amy L. Waters ; Krista R. Kelly ; Lingkun Kong ; [et al.] Année de publication : 2022 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]:A:Amblyopie:Amblyopie / thérapie
[Thésaurus Mesh]Acuité visuelle
[Thésaurus Mesh]Enfant
[Thésaurus Mesh]Essais contrôlés randomisés comme sujet
[Thésaurus Mesh]Lentilles de contactRésumé : SIGNIFICANCE: Binocular treatment for unilateral amblyopia is an emerging treatment that requires evaluation
through a randomized clinical trial.
PURPOSE: This study aimed to compare change in amblyopic-eye visual acuity (VA) in children aged 4 to 6 years
treated with the dichoptic binocular iPad (Apple, Cupertino, CA) game, Dig Rush (not yet commercially available;
Ubisoft, Montreal, Canada), plus continued spectacle correction versus continued spectacle correction alone.
METHODS: Children (mean age, 5.7 years) were randomly assigned to home treatment for 8 weeks with the iPad
game (prescribed 1 h/d, 5 d/wk [n = 92], or continued spectacle correction alone [n = 90]) in a multicenter randomized clinical trial. Before enrollment, children wearing spectacles were required to have at least 16 weeks of wear or
no improvement in amblyopic-eye VA (<0.1 logMAR) for at least 8 weeks. Outcome was change in amblyopic-eye
VA from baseline to 4 weeks (primary) and 8 weeks (secondary) assessed by masked examiner.
RESULTS: A total of 182 children with anisometropic (63%), strabismic (16%; <5Δ near, simultaneous prism and
cover test), or combined-mechanism (20%) amblyopia (20/40 to 20/200; mean, 20/63) were enrolled. After
4 weeks, mean amblyopic VA improved by 1.1 logMAR lines with binocular treatment and 0.6 logMAR lines with
spectacles alone (adjusted difference, 0.5 lines; 95.1% confidence interval [CI], 0.1 to 0.9). After 8 weeks, results
(binocular treatment: mean amblyopic-eye VA improvement, 1.3 vs. 1.0 logMAR lines with spectacles alone; adjusted difference, 0.3 lines; 98.4% CI, −0.2 to 0.8 lines) were inconclusive because the CI included both zero and
the pre-defined difference in mean VA change of 0.75 logMAR lines.
CONCLUSIONS: In 4- to 6-year-old children with amblyopia, binocular Dig Rush treatment resulted in greater improvement in amblyopic-eye VA for 4 weeks but not 8 weeks. Future work is required to determine if modifications
to the contrast increment algorithm or other aspects of the game or its implementation could enhance the treatment effect.Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Treatment of children with amblyopia / Fabrizio Bonci in OPTOMETRY TODAY, vol. 61, 04 (Aout-septembre 2021)
[article]
in OPTOMETRY TODAY > vol. 61, 04 (Aout-septembre 2021) . - p. 74-78
Titre : Treatment of children with amblyopia Type de document : article de périodique Auteurs : Fabrizio Bonci Année de publication : 2021 Article en page(s) : p. 74-78 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]:A:Amblyopie:Amblyopie / thérapie
[Thésaurus Mesh]Amblyopie
[Thésaurus Mesh]Enfant
[Thésaurus Mesh]OptométrieRésumé : This CET article outlines the options for optometric management of children with amblyopia En ligne : https://www.aop.org.uk/ot/cet/2021/07/06/treatment-of-children-with-amblyopia/ar [...] Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité O Périodique Erasme - périodiques Périodiques Disponible