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Auteur Zhuokai Li
Documents disponibles écrits par cet auteur
Ajouter le résultat dans votre panier Affiner la rechercheA Pilot Randomized Clinical Trial of Base-in Relieving Prism Spectacle Treatment of Intermittent Exotropia / Allison I. Summers in OVS : Optometry & Vision Science, Vol.100, 07 (Juillet 2023)
[article]
in OVS : Optometry & Vision Science > Vol.100, 07 (Juillet 2023)
Titre : A Pilot Randomized Clinical Trial of Base-in Relieving Prism Spectacle Treatment of Intermittent Exotropia Type de document : article de périodique Auteurs : Allison I. Summers ; David G. Morrison ; Danielle L. Chandler ; Robert J. Henderson ; Angela M. Chen ; David A. Leske ; Kimberly Walker ; Zhuokai Li ; B. Michele Melia ; Derek P. Bitner ; Sudhi P Kurup ; Megan Allen ; Paul H. Phillips ; [et al.] Année de publication : 2023 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]Adaptation biologique
[Thésaurus Mesh]Enfant
[Thésaurus Mesh]Essai contrôlé randomisé
[Thésaurus Mesh]Exotropie
[Thésaurus HELB]:Optique:lunette correctrice
[Thésaurus HELB]:Optique:PrismeMots-clés : exotropie intermittente Résumé : SIGNIFICANCE
This pilot randomized trial, the first to evaluate a specific base-in relieving prism treatment strategy for childhood intermittent exotropia, did not support proceeding to a full-scale clinical trial. Defining and measuring prism adaptation in children with intermittent exotropia are challenging and need further study.
PURPOSE
This study aimed to determine whether to proceed to a full-scale trial of relieving base-in prism spectacles versus refractive correction alone for children with intermittent exotropia.
METHODS
Children 3 years old to those younger than 13 years with distance intermittent exotropia control score of ≥2 points on the Intermittent Exotropia Office Control Scale (Strabismus 2006;14:147–150; 0 [phoria] to 5 [constant]), ≥1 episode of spontaneous exotropia, and 16 to 35∆ by prism-and-alternate-cover test, who did not fully prism adapt on a 30-minute in-office prism-adaptation test were randomized to base-in relieving prism (40% of the larger of distance and near exodeviations) or nonprism spectacles for 8 weeks. A priori criteria to conduct a full-scale trial were defined for the adjusted treatment group difference in mean distance control: “proceed” (≥0.75 points favoring prism), “uncertain” (>0 to <0.75 points favoring prism), or “do not proceed” (≥0 points favoring nonprism).
RESULTS
Fifty-seven children (mean age, 6.6 ± 2.2 years; mean baseline distance control, 3.5 points) received prism (n = 28) or nonprism (n = 29) spectacles. At 8 weeks, mean control values were 3.6 and 3.3 points in prism (n = 25) and nonprism (n = 25) groups, respectively, with an adjusted difference of 0.3 points (95% confidence interval, −0.5 to 1.1 points) favoring nonprism (meeting our a priori “do not proceed” criterion).
CONCLUSIONS
Base-in prism spectacles, equal to 40% of the larger of the exodeviations at distance or near, worn for 8 weeks by 3- to 12-year-old children with intermittent exotropia did not yield better distance control than refractive correction alone, with the confidence interval indicating that a favorable effect of 0.75 points or larger is unlikely. There was insufficient evidence to warrant a full-scale randomized trial.Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire A Randomized Trial of Binocular Dig Rush Game Treatment for Amblyopia in Children Aged 4 to 6 Years / Ruth E. Manny in OVS : Optometry & Vision Science, vol.99, 03 (Mars 2022)
[article]
in OVS : Optometry & Vision Science > vol.99, 03 (Mars 2022)
Titre : A Randomized Trial of Binocular Dig Rush Game Treatment for Amblyopia in Children Aged 4 to 6 Years Type de document : article de périodique Auteurs : Ruth E. Manny ; Jonathan M. Holmes ; Raymond T. Kraker ; Zhuokai Li ; Amy L. Waters ; Krista R. Kelly ; Lingkun Kong ; [et al.] Année de publication : 2022 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]:A:Amblyopie:Amblyopie / thérapie
[Thésaurus Mesh]Acuité visuelle
[Thésaurus Mesh]Enfant
[Thésaurus Mesh]Essais contrôlés randomisés comme sujet
[Thésaurus Mesh]Lentilles de contactRésumé : SIGNIFICANCE: Binocular treatment for unilateral amblyopia is an emerging treatment that requires evaluation
through a randomized clinical trial.
PURPOSE: This study aimed to compare change in amblyopic-eye visual acuity (VA) in children aged 4 to 6 years
treated with the dichoptic binocular iPad (Apple, Cupertino, CA) game, Dig Rush (not yet commercially available;
Ubisoft, Montreal, Canada), plus continued spectacle correction versus continued spectacle correction alone.
METHODS: Children (mean age, 5.7 years) were randomly assigned to home treatment for 8 weeks with the iPad
game (prescribed 1 h/d, 5 d/wk [n = 92], or continued spectacle correction alone [n = 90]) in a multicenter randomized clinical trial. Before enrollment, children wearing spectacles were required to have at least 16 weeks of wear or
no improvement in amblyopic-eye VA (<0.1 logMAR) for at least 8 weeks. Outcome was change in amblyopic-eye
VA from baseline to 4 weeks (primary) and 8 weeks (secondary) assessed by masked examiner.
RESULTS: A total of 182 children with anisometropic (63%), strabismic (16%; <5Δ near, simultaneous prism and
cover test), or combined-mechanism (20%) amblyopia (20/40 to 20/200; mean, 20/63) were enrolled. After
4 weeks, mean amblyopic VA improved by 1.1 logMAR lines with binocular treatment and 0.6 logMAR lines with
spectacles alone (adjusted difference, 0.5 lines; 95.1% confidence interval [CI], 0.1 to 0.9). After 8 weeks, results
(binocular treatment: mean amblyopic-eye VA improvement, 1.3 vs. 1.0 logMAR lines with spectacles alone; adjusted difference, 0.3 lines; 98.4% CI, −0.2 to 0.8 lines) were inconclusive because the CI included both zero and
the pre-defined difference in mean VA change of 0.75 logMAR lines.
CONCLUSIONS: In 4- to 6-year-old children with amblyopia, binocular Dig Rush treatment resulted in greater improvement in amblyopic-eye VA for 4 weeks but not 8 weeks. Future work is required to determine if modifications
to the contrast increment algorithm or other aspects of the game or its implementation could enhance the treatment effect.Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire Rasch-calibrated Intermittent Exotropia Symptom Questionnaire for Children / Jonathan M. Holmes in OVS : Optometry & Vision Science, vol. 99, 06 (Juin 2022)
[article]
in OVS : Optometry & Vision Science > vol. 99, 06 (Juin 2022)
Titre : Rasch-calibrated Intermittent Exotropia Symptom Questionnaire for Children Type de document : article de périodique Auteurs : Jonathan M. Holmes ; David A. Leske ; Amra Hercinovic ; Sarah R. Hatt ; Danielle L. Chandler ; Zhuokai Li ; B. Michele Melia ; Angela M. Chen ; Sergul Ayse Erzurum ; Eric R. Crouch ; Erin C. Jenewein ; Raymond T. Kraker ; Susan A. Cotter Année de publication : 2022 Langues : Français (fre) Descripteurs (mots clés) : [Thésaurus Mesh]Collecte de données
[Thésaurus Mesh]Enfant
[Thésaurus Mesh]Essais contrôlés randomisés comme sujet
[Thésaurus Mesh]Exotropie
[Thésaurus Mesh]Lunettes correctrices
[Thésaurus Mesh]Questionnaires
[Thésaurus Mesh]Signes et symptômesMots-clés : modèle de Rasch lunettes overminus lunettes non overminus Résumé : SIGNIFICANCE
A rigorously designed and calibrated symptom questionnaire for childhood intermittent exotropia would be useful for clinical care and for research.
PURPOSE
The aim of this study was to Rasch-calibrate and evaluate the previously developed Child Intermittent Exotropia Symptom Questionnaire using data gathered as part of a randomized clinical trial.
METHODS
The questionnaire was administered to 386 children aged 3 to 10 years with intermittent exotropia who were enrolled in a randomized clinical trial comparing overminus with nonoverminus spectacles. Participants were followed at 6 and 12 months while on treatment and at 18 months off treatment. Factor analysis determined dimensionality, and Rasch analysis evaluated questionnaire performance. Logit values were converted to 0 (best) to 100 (worst). We evaluated differences in questionnaire scores between treatment groups and time points, and correlations with control scores.
RESULTS
The Child Intermittent Exotropia Symptom Questionnaire was unidimensional. Rasch analysis indicated that there was no notable local dependence and no significant differential item functioning for sex or age. There was suboptimal targeting (mean logit, −1.62), and person separation was somewhat poor (0.95). There were no significant differences in the Child Intermittent Exotropia Symptom score between overminus spectacles and nonoverminus spectacles at 6, 12, and 18 months. Combining data from both treatment groups, there was significant improvement from baseline at all follow-up visits (e.g., mean change from baseline to 12 months, −6.6 points; 95% confidence interval, −8.6 to −4.6). Child Intermittent Exotropia Symptom scores were not correlated with distance or near control scores at 12 months.
CONCLUSIONS
The seven-item Rasch-scored Child Intermittent Exotropia Symptom Questionnaire is limited by suboptimal performance. Future study is needed to determine whether it may be useful for clinical practice and for research.Permalink : https://bibliotheque.helb-prigogine.be/opac_css/index.php?lvl=notice_display&id= [article]Exemplaires
Cote Support Localisation Section Disponibilité aucun exemplaire